Results 41 to 50 of about 2,059,290 (296)

From Generation to Generation [PDF]

open access: yesClinical Chemistry, 2019
This work (Fig. 1) is a geometric abstraction that I created using pencil, ink, and acrylic paint on canvas. It could be interpreted as a spatial representation of time, peering along the branches of a pedigree or phylogenetic tree. The tree consists of three main branches with “cousins” on two of the branches connected by …
openaire   +3 more sources

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Adult children migration and perceived discrimination among Indian older adults: evidence from longitudinal ageing study in India

open access: yesBMC Public Health
Background The migration of adult children significantly affects older adults’ lives in various ways. This study explores the association between adult children’s migration and perceived discrimination among older adults left behind in India. Methods The
Valatheeswaran Chinnakkannu   +3 more
doaj   +1 more source

Subjective social status and functional and mobility impairments among older adults: life satisfaction and depression as mediators and moderators

open access: yesBMC Geriatrics, 2023
Background While functional and mobility impairments (FMIs) have garnered the attention of health researchers in low and middle-income countries (LMICs), including India, research has yet to explore whether and to what extent the perception of one’s ...
Manacy Pai, T. Muhammad
doaj   +1 more source

Generations 2010 [PDF]

open access: yes, 2010
Examines trends in the prevalence of various online activities such as blogging and social networking among each generation compared with previous survey findings, with a focus on changes in the gaps between Millennials ages 18-33 and older ...
Kathryn Zickuhr
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Editorial

open access: yesIntergenerational Justice Review, 2015
None
Petter Haakenstad Godli   +5 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Bending the Clock: New Perspectives on Nineteenth-Century Ageing: A Roundtable Conversation

open access: yes19, 2021
Over the past decade, several academic studies have taken nineteenth-century ageing as their topic, including Devoney Looser’s Women Writers and Old Age in Great Britain (2008), Karen Chase’s The Victorians and Old Age (2009), Kay Heath’s Aging by the ...
Andrea Charise   +5 more
doaj   +2 more sources

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