Results 101 to 110 of about 39,370 (305)

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

Advanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng, Xinlei Huang, Xiang Zhou, Dian Meng, Ziyue Qiao, Zhiyuan Yuan, Lixin Cheng   +6 more
wiley   +1 more source

Probabilistic Generative Adversarial Networks

CoRR, 2017
We introduce the Probabilistic Generative Adversarial Network (PGAN), a new GAN variant based on a new kind of objective function. The central idea is to integrate a probabilistic model (a Gaussian Mixture Model, in our case) into the GAN framework which supports a new kind of loss function (based on likelihood rather than classification loss), and at ...
Hamid Eghbal-zadeh, Gerhard Widmer
openaire   +2 more sources

Generative Adversarial Networks and Applications in Bioinformatics

, 2021
Generative Adversarial Networks (GAN) are currently considered a state-of-the-art method for image generation. Recently, Deep Convolutional Generative Adversarial Networks (DCGAN) yielded promising results in protein contact maps generation.
KOLESNICHENKO, Nikita
core  

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

Generative Adversarial Networks for Lupus Diagnostics

, 2019
The recent boom of Machine Learning Network Architectures like Generative Adversarial Networks (GAN), Deep Convolution Generative Adversarial Networks (DCGAN), Self Attention Generative Adversarial Networks (SAGAN), Context Conditional Generative ...
Pradeep Periasamy (7242737)
core   +2 more sources

LDDMM Meets GANs: Generative Adversarial Networks for Diffeomorphic Registration

, 2021
In this work, we propose an unsupervised adversarial learning LDDMM method for 3D mono-modal images based on Generative Adversarial Networks.
Elvira Mayordomo Cámara, Mayordomo Cámara, Elvira, Ramon Julvez, Ubaldo, Hernández Giménez, Mónica, Ubaldo Ramon Julvez, Mónica Hernández Giménez   +5 more
core   +1 more source

From Label‐Free Multiphoton Imaging to Pathological Reports: A Vision‐Language Breast Cancer Margin Pathological Diagnosis System

Advanced Science, EarlyView.
MarginPath is a novel vision‐language system that automates breast cancer margin assessment using a single label‐free multiphoton microscopy image. By integrating tumor‐associated collagen signatures with virtual H&E imaging, it generates accurate margin heatmaps and comprehensive diagnostic reports.
Shu Wang, Jingze Su, Xiahui Han, Deyong Kang, Xiao Zhang, Fei Xu, Changzu Liu, Junlin Pan, Xingfu Wang, Qiaohui Zhan, Aimin Wang, Feng Huang, Heping Cheng, Wenxi Liu, Ruolan Lin, Jianxin Chen   +15 more
wiley   +1 more source

Coevolution of Generative Adversarial Networks [PDF]

, 2019
Published in EvoApplications ...
Victor Costa, Nuno Lourenço 0002, Penousal Machado   +2 more
openaire   +2 more sources

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Optimizing distributions over molecular space. An Objective-Reinforced Generative Adversarial Network for Inverse-design Chemistry (ORGANIC)

, 2017
Molecular discovery seeks to generate chemical species tailored to very specific needs. In this paper, we present ORGANIC, a framework based on Objective-Reinforced Generative Adversarial Networks (ORGAN), capable of producing a distribution over ...
Gabriel L., Guimaraes, Benjamin, Sanchez-Lengeling, Carlos, Outeiral, Alan, Aspuru-Guzik   +3 more
core   +1 more source