Results 121 to 130 of about 1,527,016 (289)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
A Primer on Generative Artificial Intelligence
Education SciencesMany educators and professionals in different industries may need to become more familiar with the basic concepts of artificial intelligence (AI) and generative artificial intelligence (Gen-AI).
Faisal Kalota
doaj +1 more source
A Comprehensive Survey on Generative AI for Metaverse: Enabling Immersive Experience
Generative Artificial Intelligence models are Artificial Intelligence models that generate new content based on a prompt or input. The output content can be in various forms, including text, images, and video.
Hussain, Amir +7 more
core +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Tissue Reassembly with Generative AI
The spatial arrangement of cells plays a critical role in determining their functions and interactions within tissues. However, single-cell RNA sequencing dissociates cells from their native tissue context, resulting in a loss of spatial information ...
Yu, Tingyang +6 more
core
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Based on a case study of ChatGPT-4’s ability to solve a third-semester BA exam question in Logic and Argumentation Theory, this article argues that students should be encouraged to reason alongside ChatGPT. Echoing previous findings, we confirm that while ChatGPT demonstrates impressive linguistic abilities, including skills in formalizing arguments ...
openaire +1 more source
Generative AI in Medical Practice: In-Depth Exploration of Privacy and Security Challenges
Journal of Medical Internet ResearchAs advances in artificial intelligence (AI) continue to transform and revolutionize the field of medicine, understanding the potential uses of generative AI in health care becomes increasingly important. Generative AI, including models such as
Yan Chen, Pouyan Esmaeilzadeh
doaj +1 more source
Generative AI and the creative industries
Partecipazione programmata, in data 28 e 29 novembre 2024, al Convegno Internazionale “Generative AI and the creative industries” presso la Scuola di Studi Superiori “Ferdinando Rossi” dell’Università degli Studi di ...
Orlando, Luca, Natale, Simone
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source