Results 231 to 240 of about 22,229,619 (357)

A Deep Generative Model for the Inverse Design of Transition Metal Ligands and Complexes. [PDF]

JACS Au
Strandgaard M, Linjordet T, Kneiding H, Burnage AL, Nova A, Jensen JH, Balcells D.   +6 more
europepmc   +1 more source

Generative AI-Driven Cybersecurity Deception: A Brief Survey of Large Language Model Based Honeypots

Vibhutesh Kumar Singh
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A mixture of attention experts-embedded flow-based generative model to create synthetic cells in single-cell RNA-Seq datasets. [PDF]

PLoS Comput Biol
Turgut Ögme SS, Aydin N, Kurt Z.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Implementation of a Conditional Latent Diffusion-Based Generative Model to Synthetically Create Unlabeled Histopathological Images. [PDF]

Bioengineering (Basel)
Rumman MI, Ono N, Ohuchida K, Nasution AK, Alqaaf M, Altaf-Ul-Amin M, Kanaya S.   +6 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Correction for Richter and Schneidman, Building the connectome of a small brain with a simple stochastic developmental generative model. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

A generative model of the connectome with dynamic axon growth. [PDF]

Netw Neurosci
Liu Y, Seguin C, Betzel RF, Han D, Akarca D, Di Biase MA, Zalesky A.   +6 more
europepmc   +1 more source

Fine-Tuned 'Small' LLMs (Still) Significantly Outperform Zero-Shot Generative AI Models in Text Classification [PDF]

Martin Juan José Bucher, Marco Martini
openalex   +1 more source