Results 211 to 220 of about 185,676 (265)

Probabilistic brain MR image transformation using generative models. [PDF]

Sci Rep
Rezvani S, Moazami S, Azevedo CJ, Oberai AA.   +3 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Generative models and synthetic data in clinical prediction models: Promoting consistency, reproducibility, and transparency. [PDF]

J Clin Transl Sci
Mangino AA, Ahmed T, Sorrell VL.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Deepfake-induced harm and AI accountability: a layered civil-liability framework for generative models, platforms, and digital identity. [PDF]

Front Artif Intell
Abousud EA.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Author Correction: Generalizable and scalable protein stability prediction with rewired protein generative models. [PDF]

Nat Commun
Li Z, Luo Y.
europepmc   +1 more source

Blue Noise-based Generative Models for the Imputation of Time-series Data. [PDF]

Int Conf Inf Sci Technol
Bishop G, Si T, Gong H.
europepmc   +1 more source

Generalizable and scalable protein stability prediction with rewired protein generative models. [PDF]

Nat Commun
Li Z, Luo Y.
europepmc   +1 more source

ABaCo: addressing heterogeneity challenges in metagenomic data integration with adversarial generative models. [PDF]

Nucleic Acids Res
Vidal E, Phanthanourak AL, Gharib A, Webel H, Assis J, Ayala-Ruano S, Cunha AF, Santos A.   +7 more
europepmc   +1 more source