Results 221 to 230 of about 1,241,853 (284)

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

Advanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui, Beibei Zhang, Jiaxi Tang, Jing Hou, Yueqin Qiu, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang   +8 more
wiley   +1 more source

Quality of life effects of renal artery stenting versus medical therapy for atherosclerotic renal-artery stenosis: results from the randomized CORAL trial. [PDF]

Eur Heart J Qual Care Clin Outcomes
Arnold SV, Wang K, Kirtane AJ, Magnuson EA, Chinnakondepalli KM, Cooper CJ, Dworkin LD, Cohen DJ.   +7 more
europepmc   +1 more source

G4‐Ligand‐Directed PROTACs Unveil DR1 as a Novel Ligand‐Co‐Binding G4‐Protein and Reshape G4‐Dependent Transcription

Advanced Science, EarlyView.
G4‐binding proteins (G4BPs) that specifically co‐bind G4s in the presence of small‐molecule ligands represent a critical but unexplored class of proteins. We introduce G4‐Ligand‐Directed PROTACs (G4L‐TACs), a chemical platform that couples G4 ligands (PDS) to E3 recruiters to selectively degrade these ligand‐co‐binding G4BPs.
Mao‐Lin Li, Shu‐Min Xu, Xin‐Chen Jiang, Le‐Tian Dai, Yu‐Tao Hu, Kai‐Bo Wang, Jia‐Heng Tan, Zhi‐Shu Huang, Shuo‐Bin Chen   +8 more
wiley   +1 more source

Hypothetical nudges provide directional but noisy estimates of real behavior change. [PDF]

Commun Psychol
Gandhi L, Kiyawat A, Camerer C, Watts DJ.   +3 more
europepmc   +1 more source

Beyond the Non‐Hermitian Skin Effect: Scaling‐Controlled Topology from Exceptional‐Bound Bands

Advanced Science, EarlyView.
ABSTRACT We establish a novel mechanism for topological transitions in non‐Hermitian systems that are controlled by the system size. Based on a new paradigm known as exceptional‐bound (EB) band engineering, its mechanism hinges on the unique critical scaling behavior near an exceptional point, totally unrelated to the well‐known non‐Hermitian skin ...
Mengjie Yang, Ching Hua Lee
wiley   +1 more source

Layer-based personalized multi-fusion federated learning. [PDF]

Sci Rep
Yang W, Chen B, Wang Z.
europepmc   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Trends in paediatric antiseizure-medication use and costs in France, 2014-2023: a nationwide population-based analysis. [PDF]

Lancet Reg Health Eur
Nabbout R, Santilli A, Tyvaert L, Schweitzer C, Maillard L, Kuchenbuch M.   +5 more
europepmc   +1 more source

Physical Implementation of Optical Material‐Based Neural Networks Processing Enabled by Long‐Persistent Luminescence

Advanced Science, EarlyView.
This study reports on the physical implementation of optical material‐based neural processing using long‐persistent luminescence as memory‐retention and nonlinear optical material. The system performs optical‐domain preprocessing with opto‐electronic interfaces for stimulus delivery and readout, enabling real‐time demonstrations including Pong gameplay
Sangwon Wi, Yunsang Lee
wiley   +1 more source

Pulmonary Arterial Hypertension and Cancer: Unveiling Parallels in Epidemiology, Clinical Pathways, and Therapeutic Strategies. [PDF]

J Mark Access Health Policy
El-Kersh K, Zawadzki N, Coyle C, Zhang S, Dalal D, Watzker A, Lautsch D, Shafrin J.   +7 more
europepmc   +1 more source