Results 191 to 200 of about 513,714 (276)

The Future of Biologics: Lessons from Hatch-Waxman. [PDF]

Ther Innov Regul Sci
Miller BJ, Woodcock J.
europepmc   +1 more source

What a Loaded Generalization: Generics and Social Cognition

, 2015
Daniel Wodak, S. Leslie, Marjorie Rhodes
semanticscholar   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

Advanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park, Yeongkag Kwon, Yeonjin Lim, Jeong Woo Park, Hyun Jung Ji, Dongwook Lee, Jueun Lee, Sung‐Ho Yun, Sungho Jeong, Ho Seong Seo, Kun Cho, Cheol‐Heui Yun, Ok‐Jin Park, Seung Hyun Han   +13 more
wiley   +1 more source

Investigating the Impact of Food Induced Fluid Viscosity on Disintegration and Dissolution of Immediate Release Midodrine HCl Tablet. [PDF]

AAPS J
Doole FT, Don RW, Poudel I, Lex T, Cheng YH, Wu F, Sun WJ, Zhang L, Langguth P, Jiang W, Gao Z.   +10 more
europepmc   +1 more source

Leslie on generics

, 2015
R. Sterken
semanticscholar   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Balancing policy ambition and systems reality in expanding access to non-communicable diseases medicines: lessons from Ghana and Georgia. [PDF]

Health Policy Plan
Koduah A, Zoidze A, Uchaneishvili M, Novignon J, Murphy A, Palafox B, Mirzoev T, Gotsadze G.   +7 more
europepmc   +1 more source

Bidirectional Soft Catalysts for Improved Power Performance of Li‐S Batteries

Advanced Science, EarlyView.
A soft polymer‐metal catalyst is integrated into the binder to create a catalytically active microenvironment that accelerates bidirectional sulfur redox kinetics in lithium‐sulfur batteries. A model polyvinyl alcohol‐Cu catalyst enables high areal capacities at demanding current densities and stable cycling in pouch‐cell prototypes at 0.5 C, achieving
Maleesha M. Nishshanke, Petar Jovanovic, Swarit Dwivedi, Declan McNamara, Akshat Tanksale, Mahdokht Shaibani, Matthew Hill, Mainak Majumder   +7 more
wiley   +1 more source

Increasing competition in pharmaceutical tenders: Patents, treatment guidelines, and centralised procurement of Hepatitis C drugs in Brazil. [PDF]

Glob Public Health
Mercadante E.
europepmc   +1 more source