Results 241 to 250 of about 480,989 (325)

Harmonizing health: a global analysis of pharmaceutical regulatory activities by international regulatory organizations. [PDF]

Front Med (Lausanne)
Dangy-Caye A, Mousset A, Kermad A, Bouché-Bazerolle L, Bujar M, De Lucia ML, McAuslane N, Lumsden R.   +7 more
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

U.S. International AIDS Programs: A New Model of Humanitarian Initiatives? [PDF]

, 2006
Dietrich, John W.
core   +1 more source

Sulfate‐Directed Silver Dendrites with Enhanced Stability for Ultrasensitive SERS‐Based Therapeutic Drug Monitoring

Advanced Science, EarlyView.
This study presents sulfate‐directed silver dendrites (s‐AgDs) as oxidation‐resistant SERS substrates with long‐term stability, reproducibility, and sub‐picomolar sensitivity. Sulfate ions guide anisotropic growth and protect the surface, enabling improved performance over 7 months under ambient conditions.
Aradhana Dwivedi, Jan Dellith, Anna Makarova, Samir F. El‐Mashtoly, Juergen Popp, Vladimir Sivakov, Dana Cialla‐May   +6 more
wiley   +1 more source

On paper; in practice: measuring compliance with official pricing policies in a large field study of essential medicines in Indonesia. [PDF]

J Pharm Policy Pract
Rahmawati A, Ramadaniati HU, Anggriani Y, Nathanial W, Pisani E.   +4 more
europepmc   +1 more source

Hydrogen‐Bonding Networks Enabled by Trace Water for Morphological Design in Ternary Organic Solar Cells

Advanced Science, EarlyView.
Trace water transforms from an impurity to a design handle for ternary organic solar cells. During solvent evaporation, minimal amounts organize transient hydrogen‐bonding networks that steer component migration and set the morphology. The mechanism enables reproducible morphology locking and identifies a practical co‐solvent threshold near H2O:CF = 0 ...
Yue Ren, Ming‐Yue Sui, Yun Geng, Rui‐Cheng Qin, Ming‐Yang Li, Guang‐Yan Sun, Xin Xu   +6 more
wiley   +1 more source

Savings from biosimilars and Medicare formulary access. [PDF]

Health Aff Sch
Axelsen K, Courmier D, Bai G, Maini L.
europepmc   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Drug shortages: clinical implications and burdens - a trinational multiple-methods study including key stakeholders. [PDF]

J Pharm Policy Pract
Rose O, Hoti K, Isufi B, Wachinger M, Pachmayr J, Hartl A, Giesen H, Clemens S.   +7 more
europepmc   +1 more source