Results 111 to 120 of about 102,801 (342)

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

From the light triad to the dark tetrad: Two sides of human nature in the context of life and health, considering cognitive reflection and generosity

Fides et Ratio
This article reviews research on two contrasting groups of personality traits – from the so-called light triad (including faith in humanity, humanism, and Kantianism) to the so-called Dark Tetrad (including Machiavellianism, narcissism, psychopathy, and ...
Marcin Kusiak
doaj   +1 more source

Compulsory activation of young welfare recipients: revisiting the trade-off between workfare and welfare generosity

, 2023
Bård Smedsvik, Roberto Iacono
openalex   +2 more sources

Overwhelming generosity [PDF]

British Dental Journal, 2013
openaire   +2 more sources

Directing the Mobility of Guest Molecules in Nanoporous Materials by Linearly Polarized Light

Advanced Science, EarlyView.
The polarization of light is introduced as a further parameter to dynamically and reversibly control the properties of a photoresponsive nanoporous material. It was used to control the mobility of the guest molecules in the pores of a metal–organic framework.
Taher Al Najjar, Chun Li, Yunzhe Jiang, Anna Mauri, Modan Liu, Abhinav Chandresh, Anemar Bruno Kanj, Dragos Mutruc, Wolfgang Wenzel, Stefan Hecht, Mariana Kozlowska, Lars Heinke   +11 more
wiley   +1 more source

Little evidence that androstadienone affects social distance-dependent prosocial behaviour: a pre-registered study

Royal Society Open Science
In navigating the complexities of social life, humans have evolved to interpret invisible odorous chemical cues, with profound behavioural impacts often unbeknown to the conscious mind.
Junsong Lu, Yuting Ye, Yin Wu
doaj   +1 more source

Different Leaders in a COVID-19 Scenario: CEO Altruism and Generous Discourse [PDF]

, 2021
Isabel Sánchez, Víctor Amor‐Esteban, Alejandra García-Sánchez   +2 more
openalex   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

Changes in Drug Coverage Generosity and Untreated Serious Mental Illness

, 2015
Jeanne M. Madden, Alyce S. Adams, Robert F. LeCates, Dennis Ross‐Degnan, Fang Zhang, Haiden A. Huskamp, Daniel Gilden, Stephen B. Soumerai   +7 more
openalex   +2 more sources