Results 251 to 260 of about 5,250,240 (290)

Luciferases as Reporter Genes

2006
Luciferase is the ideal reporter gene to provide temporal and spatial information on promoter activity in Arabidopsis and other eukaryotes; the noninvasive detection of luminescence and short half-life of luciferase activity allow repeated measurements of individual seedlings over several days to assay dynamic changes in gene expression.
Megan M, Southern, Paul E, Brown, Anthony, Hall   +2 more
openaire   +2 more sources

Reporter Gene Vectors and Assays

Molecular Biotechnology, 1999
Gene reporter systems play a key role in gene expression and regulation studies. This review describes the ideal reporter systems, including reporter expression vector design. It summarizes the many uses of genetic reporters and outlines the currently available and commonly used reporter systems.
E, Schenborn, D, Groskreutz
openaire   +2 more sources

Gene manipulation success reported

Nursing Standard, 1990
For the first time foreign genes have been inserted into the human body.
openaire   +2 more sources

Reporter genes in transgenic mice

Transgenic Research, 1994
Although in vivo models utilizing endogenous reporter genes have been exploited for many years, the use of reporter transgenes to dissect biological issues in transgenic animals has been a relatively recent development. These transgenes are often, but not always, of prokaryotic origin and encode products not normally associated with eukaryotic cells ...
C, Cui, M A, Wani, D, Wight, J, Kopchick, P J, Stambrook   +4 more
openaire   +2 more sources

Radionuclide reporter gene imaging for cardiac gene therapy

European Journal of Nuclear Medicine and Molecular Imaging, 2007
In the field of cardiac gene therapy, angiogenic gene therapy has been most extensively investigated. The first clinical trial of cardiac angiogenic gene therapy was reported in 1998, and at the peak, more than 20 clinical trial protocols were under evaluation.
Masayuki, Inubushi, Nagara, Tamaki
openaire   +2 more sources

Reporter Gene Assays in Ecotoxicology

2016
The need for simple and rapid means for evaluating the potential toxic effects of environmental samples has prompted the development of reporter gene assays, based on tester cells (bioreporters) genetically engineered to report on sample toxicity by producing a readily quantifiable signal. Bacteria are especially suitable to serve as bioreporters owing
Tal, Elad, Shimshon, Belkin
openaire   +2 more sources

Molecular Imaging: Reporter Gene Imaging

2008
Non-invasive in-vivo molecular genetic imaging developed over the past decade and predominantly utilises radiotracer (PET, gamma camera, autoradiography), magnetic resonance and optical imaging technology. Molecular genetic imaging has its roots in both molecular biology and cell biology.
Inna, Serganova, Phillipp, Mayer-Kukuck, Ruimin, Huang, Ronald, Blasberg   +3 more
openaire   +2 more sources

The GUS reporter gene system

Nature, 1989
The GUS reporter gene system is already a powerful tool for the assessment of gene activity in transgenic plants. Further developments may lead to routine in vivo analysis and fusion genetics.
openaire   +2 more sources

Radionuclide Gene and Reporter Gene Imaging

2019
In the 1970s, the Johns Hopkins University School of Medicine (JHUSOM) and Harvard Medical School discovered that antisense oligonucleotides (ASON) could actually block the expression of specific genes. Since then, a new genetic engineering technology—antisense technology—has emerged.
Xiaoli Lan, Min Ye, Pengxin Qiao, Wenxia Wang   +3 more
openaire   +1 more source

Aequorin as a Reporter Gene

2006
Reporter proteins allow one to monitor cellular parameters that are involved in signal transduction, development, metabolic processes, and transport. There are targeting strategies available to direct the indicator protein exactly to the locale inside the organism from which information is desired.
openaire   +2 more sources