Results 261 to 270 of about 12,090,697 (382)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Problemas en la vestimenta en personas con discapacidad

Medicina Clínica y Social, 2019
Iván Barrios, Aaron Genes
doaj  

Gene association study between polycystic ovary syndrome and metabolic syndrome: a transcriptomic analysis and machine learning approach. [PDF]

J Ovarian Res
Xu H, Mao L, Huang W, Huang Q, Li L, Liu Y.   +5 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Assessing Evolutionary Divergence in Genome-Wide MADS-Box Genes and Expression Profiles Between <i>Toona ciliata</i> and <i>Toona sinensis</i>. [PDF]

Ecol Evol
Liu XH, Xiao Y, Lv YW, Wang ZY, Wu C, Xie H, Hu XS.   +6 more
europepmc   +1 more source

GENE ACTION AND POSITION EFFECT IN DUPLICATIONS IN DROSOPHILA MELANOGASTER [PDF]

, 1954
F.J. Ratty
openalex   +1 more source

Interferon-stimulated genes: a complex web of host defenses.

Annual Review of Immunology, 2014
W. Schneider, Meike Chevillotte, C. Rice
semanticscholar   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Chromatin accessibility and gene expression in the parasite Trichomonas vaginalis. [PDF]

BMC Infect Dis
Prat A, Muñoz D, Lizarraga A, Seifert-Gorzycki J, Sanchez-Vazquez E, Johnson PJ, Strobl-Mazzulla PH, de Miguel N.   +7 more
europepmc   +1 more source

ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences.

Nucleic Acids Research, 2004
D. Laslett, B. Canback
semanticscholar   +1 more source