Results 11 to 20 of about 6,238,924 (364)
The Genetics of Spondyloarthritis [PDF]
Journal of Personalized Medicine, 2020 The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases with common features in terms of clinical presentation and genetic predisposition. SpA is characterized by inflammation of the spine and peripheral joints, and is also be associated with extra-articular inflammatory manifestations such as psoriasis, uveitis, or ...
Roberto Díaz-Peña +4 more
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Biological Reviews, 2017 ABSTRACTDispersal is a process of central importance for the ecological and evolutionary dynamics of populations and communities, because of its diverse consequences for gene flow and demography. It is subject to evolutionary change, which begs the question, what is the genetic basis of this potentially complex trait?
Hanna Kokko +23 more
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Psychiatric Genetics Before “Genetics” [PDF]
American Journal of Psychiatry, 2021 I write this in terrible times. Across the world, a pandemic rages nearly unchecked when simple behavioral changes could save many lives. Psychiatric disorders and their sequalae have sharply increased. The role of science, logic, data, and expertise have been pushed to the curb in favor of those who shout loudest.
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Science, 2011 Systems genetics is the next frontier in systems biology and medicine.
Joseph H. Nadeau, Aimée M. Dudley
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Genetics of osteoporosis [PDF]
Annals of the New York Academy of Sciences, 2007 Osteoporosis is a common disease with a strong genetic component characterized by reduced bone mass and an increased risk of fragility fractures. Twin and family studies have shown that the heritability of bone mineral density and other determinants of fracture risk, such as ultrasound properties of bone, skeletal geometry, and bone turnover, is high ...
Stuart H. Ralston +1 more
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Genetic modification and genetic determinism. [PDF]
Philosophy, ethics, and humanities in medicine : PEHM, 2006 In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism.
David B. Resnik, Daniel Vorhaus
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Genetics of the epilepsies [PDF]
Current Opinion in Pediatrics, 1999 Summary: Recent molecular insights into the human idiopathic epilepsies have suggested the central role of ligand‐gated and voltage‐gated ion channels in their etiology. So far, genes coding for sodium and potassium channel subunits as well as a nicotinic cholinergic receptor subunit have been identified for mendelian idiopathic epilepsies.
Ingrid E. Scheffer, Samuel F. Berkovic
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Nature vs. nurture: FOXP3, genetics, and tissue environment shape Treg function
Frontiers in Immunology, 2022 The importance of regulatory T cells (Tregs) in preventing autoimmunity has been well established; however, the precise alterations in Treg function in autoimmune individuals and how underlying genetic associations impact the development and function of ...
Arielle Raugh +3 more
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Research Journal of Life Science, 2015 Research with aim to estimate genetic polymorphism at ACACA (Acetyl-coenzyme A carboxylase ) locus in Ettawa Crossbred goat wan its relationship with production traits was done at goat population in Batu, Lawang and Ampel Gading.
Sucik Maylinda +2 more
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EPCR Gene Ser219Gly Polymorphism and Venous Thromboembolism: A Meta-Analysis of 9,494 Subjects
Frontiers in Physiology, 2017 Background: Although endothelial cell protein C receptor (EPCR) gene Ser219Gly polymorphism has been associated with venous thromboembolism (VTE) susceptibility, no clear consensus has yet been reached.Objective and methods: A meta-analysis of 9,494 ...
Yan-yan Li +6 more
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