Results 351 to 360 of about 9,996,988 (405)

Genetics and reverse genetics of rotavirus

Current Opinion in Virology, 2012
Rotavirus is a member of the family Reoviridae, which have genomes consisting of 10-12 double-stranded RNA segments. The functions of proteins encoded by each segment of the rotavirus genome have been studied extensively by several methods including reassortants, temperature-sensitive mutants, isolates with rearranged RNA segments, RNAi analysis, and ...
Satoshi Komoto, Koki Taniguchi
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PowerMarker: an integrated analysis environment for genetic marker analysis

Bioinform., 2005
SUMMARY PowerMarker delivers a data-driven, integrated analysis environment (IAE) for genetic data. The IAE integrates data management, analysis and visualization in a user-friendly graphical user interface.
Kejun Liu, S. Muse
semanticscholar   +1 more source

Development and validation of a genetic algorithm for flexible docking.

Journal of Molecular Biology, 1997
Prediction of small molecule binding modes to macromolecules of known three-dimensional structure is a problem of paramount importance in rational drug design (the "docking" problem).
G. Jones, P. Willett, R. Glen, Andrew R. Leach, Robin Taylor   +4 more
semanticscholar   +1 more source

Genetics and Genetic Counselling

1971
In man the genetic code is carried in the nuclear deoxyribonucleic acid (D.N.A.). This D.N.A. is present as long helical double filaments in the chromosomes. The sequence of nucleic acids in these D.N.A. strands determines the nature of the cell proteins and hence the structure and function of the cell.
Jack M. Slater, Alastair W. Blair, Gifford F. Batstone   +2 more
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Genetic Analysis

1998
The Mendelian analysis of genetic variation, available as induced mutants or as natural variation, requires a number of steps that are described in this chapter. These include the determination of the number of genes involved in the observed trait's variation, the determination of dominance relationships between alleles of the same locus, and epistatic
Koornneef, M., Alonso-Blanco, C., Stam, P.   +2 more
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Genetics in medicine and medicine in genetics

The American Journal of Medicine, 1963
Abstract The role of genetics in medicine is discussed in the framework of diagnosis, prognosis and treatment. The role of medicine in the advancement of genetics is illustrated with a list of ten leading discoveries in human genetics.
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The Genetics of Schizophrenia is the Genetics of Neurodevelopment

British Journal of Psychiatry, 1991
Genes are now accepted as being important in the aetiology of schizophrenia (Gottesman & Shields, 1982; McGuffinet al,1987), and over the past decade the emphasis in genetic research has shifted away from genetic epidemiology to searching the chromosomal DNA for the genes themselves. Despite this increasing technical sophistication, the application
Peter B. Jones, Robin M. Murray
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Genetic counselling and the new genetics

Trends in Genetics, 1988
Abstract The mapping of most important human disease genes has already been accomplished, promising epochal changes in health care and disease prevention. This article explores the potential benefits and dangers, emphasizing the high priority that must be given to non-directive genetic counselling.
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Genetic imprinting in clinical genetics

Development, 1990
ABSTRACT Genetic, and indeed genomic, imprinting does occur in humans. This is manifest at the level of the genome, the individual chromosome, subchromosomal region or fragile site, or the single locus. The best evidence at the single gene level comes from a consideration of familial tumour syndromes.
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Conservation Genetics

Annual Review of Genetics, 1995
Inbreeding depression, accumulation and loss of deleterious mutations, loss of genetic variation in small populations, genetic adaptation to captivity and its effect on reintroduction success, and outbreeding depression are reviewed. The impact of genetic factors in endangerment and extinction has been underestimated in some recent publications ...
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