Results 221 to 230 of about 206,658 (295)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Genetic diversity and agromorphological characterization of Fenugreek (Trigonella foenum-graecum L.) germplasm provides insight for breeding and crop improvement. [PDF]
Meena VS +5 more
europepmc +1 more source
Variability, heritability, genetic advance and path analysis in yam bean (Pachyrhizus erosus L.) [PDF]
H.V. Singh +3 more
openalex
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Motivations for obtaining advance provision of medication abortion in the United States: a qualitative study. [PDF]
Johnson DM +3 more
europepmc +1 more source
Genetic Advance, Heritability and Correlation Estimate in Some Melon Genotypes for Yield Improvement
openalex +1 more source

