Results 121 to 130 of about 4,528,698 (293)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
, 1999 The paper presents a two-level learning method for radial basis function (RBF) networks. A regularized orthogonal least squares (ROLS) algorithm is employed at the lower level to construct RBF networks while the two key learning parameters, the ...
Luk, B.L., Wu, Y., Chen, S.
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
A hybrid genetic algorithm for solving a layout problem in the fashion industry. [PDF]
As of this writing, many success stories exist yet of powerful genetic algorithms (GAs) in the field of constraint optimisation. In this paper, a hybrid, intelligent genetic algorithm will be developed for solving a cutting layout problem in the Belgian ...
Put, Ferdinand +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
تطبیق طریقة Polyalphabetic Substitution Cipher باستخدام الخوارزمیة الجینیة
Al-Rafidain Journal of Computer Sciences and Mathematics, 2008 Ghusoon Salim Basheer
doaj +1 more source
A Grouping Genetic Algorithm for the Order Batching Problem in Distribution Warehouses [PDF]
Order picking is a warehouse function that deals with the retrieval of articles from their storage locations in order to satisfy certain customer demands. Combining several single customer orders into one (more substantial) picking order can increase the
Sören Koch, Gerhard Wäscher
core
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source