Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer +8 more
wiley +1 more source
Enhanced backpropagation neural network accuracy through an improved genetic algorithm for tourist flow prediction in an ecological village. [PDF]
Chen X, Wong CUI, Zhang H, Song Z.
europepmc +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
MskAge-An Epigenetic Biomarker of Musculoskeletal Age Derived From a Genetic Algorithm Islands Model. [PDF]
Green DC +8 more
europepmc +1 more source
The contrast in upper mantle shear-wave velocity between the east european platform and tectonic Europe obtained with genetic algorithm inversion of rayleigh-wave group dispersion [PDF]
Anthony Lomax, Roel Snieder
openalex +1 more source
Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani +4 more
wiley +1 more source
Improvement of medical images with multi-objective genetic algorithm and adaptive morphological transformations. [PDF]
Moradzadeh S, Mehrdad V.
europepmc +1 more source
Structure Organization of Hierarchical Fuzzy Model Using Genetic Algorithm
Toshio Fukuda +2 more
openalex +1 more source
3D‐Printed Architected Material for the Generation of Foam‐Based Protective Equipment
This study investigates 3D‐printed architected structures as alternatives to traditional foams in protective gear. It focuses on customizing impact strength and damping through design and manufacturing integration. Testing shows these structures outperform conventional foams, offering enhanced customizability, lower weight, and tunable performance ...
Ali Zolfagharian +5 more
wiley +1 more source
Clinical outcome prediction in pediatric respiratory infections using hybrid feature selection and a genetic algorithm-optimized machine learning. [PDF]
Madhalaimuthu S, Radhakrishnan S.
europepmc +1 more source

