Results 21 to 30 of about 58,336 (216)

Integrating Developed Evolutionary Algorithm and Taguchi Method for Solving Fuzzy Facility’s Layout Problem

Fuzzy Optimization and Modeling, 2021
The quadratic assignment problem (QAP) is one of the combinatorial optimization problems belonging to the NP-hard problems’ class and has a wide application in the placement of facilities.
Hossein Jafari, Abbas Sheykhan
doaj   +1 more source

Optimizing additive manufacturing path pattern for Ti-6Al-4V thin rods using a combinatorial radial basis function surrogate-assisted genetic algorithm

Materials & Design, 2023
Path pattern is one of the most significant parameters in the additive manufacturing (AM) process because it influences the specimen's final shape and residual stress distribution.
Ruqing Bai, Guan Liang, Hao Cheng, Hakim Naceur, Daniel Coutellier, Jinglei Zhao, Jun Luo, Huayan Pu, Jin Yi   +8 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Improved Genetic Algorithm for Web Service Composition QoS Optimization [PDF]

Jisuanji gongcheng, 2017
An improved Genetic Algorithm(GA) for Web service composition Quality of Service(QoS) optimization is brought up by combining Simulated Annealing(SA) algorithm and traditional GA.In order to keep the diversity of the population,the thought of choosing ...
OUYANG Chao,CHEN Zhibo,SUN Guodong
doaj   +1 more source

A Mixed Algorithm for Integrated Scheduling Optimization in AS/RS and Hybrid Flowshop

Energies, 2022
The integrated scheduling problem in automated storage and retrieval systems (AS/RS) and the hybrid flowshop is critical for the realization of lean logistics and just-in-time distribution in manufacturing systems.
Jiansha Lu, Lili Xu, Jinghao Jin, Yiping Shao   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

The effect of intersection vehicle scheduling based on the service system of sensors and intelligent traffic road information

Discover Artificial Intelligence
With the high-speed development of the automobile industry, the number of domestic vehicles has increased significantly, which has posed a great challenge to the efficiency of road access.
Qun Wang
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source