Results 111 to 120 of about 3,829,483 (294)

Genetic Algorithm Based Feature Selection Technique for Electroencephalography Data

open access: yesApplied Computer Systems, 2019
High dimensionality is a well-known problem that has a huge number of highlights in the data, yet none is helpful for a particular data mining task undertaking, for example, classification and grouping. Therefore, selection of features is used frequently
Ali Tariq   +2 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

The Table: An Illustration of Evolutionary Design using Genetic Algorithms [PDF]

open access: yes, 1995
This paper describes an attempt to enable computers to generate truly novel conceptual designs of solid objects by using genetic algorithms (GAs). The current capabilities of the system are illustrated by the example of designing a table.
Wakefield, Jonathan P.   +1 more
core   +2 more sources

Integration of Biosemiotics and Genetic Algorithms

open access: yesStudies in Logic, Grammar and Rhetoric
This paper explores the integration of genetic algorithms (GAs) with biosemiotic concepts. It presents an overview of GAs and outlines their limitations. Then, it introduces biosemiotic principles and discusses their integration with GAs.
Sarosiek Anna, Krzanowski Roman
doaj   +1 more source

Deterministic Parameter Control Methods for Genetic Algorithms: Benchmarking on Test Functions and Boost Converter Design Optimisation

open access: yesApplied Sciences
Genetic Algorithms (GAs) are pillars of evolutionary computing and one of the most well-known population-based metaheuristic optimisation techniques. They are widely used in engineering and applied optimisation problems for their capabilities in finding ...
Cagatay Cebeci, Oğuzhan Timur
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

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