Results 1 to 10 of about 4,976,022 (186)

Exploring the gut microbiota in patients with pre-diabetes and treatment naïve diabetes type 2 - a pilot study

open access: yesBMC Endocrine Disorders, 2023
Background Compared to their healthy counterparts, patients with type 2 diabetes (T2D) can exhibit an altered gut microbiota composition, correlated with detrimental outcomes, including reduced insulin sensitivity, dyslipidemia, and increased markers of ...
Kristin Gravdal   +6 more
doaj   +1 more source

Rare and common variant discovery by whole-genome sequencing of 101 Thoroughbred racehorses

open access: yesScientific Reports, 2021
The Thoroughbred breed was formed by crossing Oriental horse breeds and British native horses and is currently used in horseracing worldwide. In this study, we constructed a single-nucleotide variant (SNV) database using data from 101 Thoroughbred ...
Teruaki Tozaki   +7 more
doaj   +1 more source

Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats

open access: yesNature Communications, 2021
The uptake of donor pluripotent stem cells (PSCs) in hosts of different species and subsequent germline transmission is very inefficient. Here, the authors show, using Prdm14 gene depleted rat host blastocysts to remove functional sperm, that germline ...
Toshihiro Kobayashi   +13 more
doaj   +1 more source

Is microbiota characterization a useful tool in clinical practice? An exploratory analysis of patients from the IBS – constant-care e-health monitoring initiative [PDF]

open access: yesMicrobiota in Health and Disease, 2023
Objective: Intestinal microbiota are prominent in the etiology of irritable bowel syndrome (IBS). In this exploratory study, we investigated short- and long-term changes in the microbiota of IBS patients after intervening with a low-FODMAP diet (LFD) or ...
M. Qais Al-sheikh   +7 more
doaj   +1 more source

Genetic diversity and effective population sizes of thirteen Indian cattle breeds

open access: yesGenetics Selection Evolution, 2021
Background The genetic structure of a diverse set of 15 Indian indigenous breeds and non-descript indigenous cattle sampled from eight states was examined, based on 777 k single nucleotide polymorphism (SNP) genotypes obtained on 699 animals, with sample
Eva M. Strucken   +5 more
doaj   +1 more source

Genome-wide identification and analysis of DNA methyltransferase and demethylase gene families in Dendrobium officinale reveal their potential functions in polysaccharide accumulation

open access: yesBMC Plant Biology, 2021
Background DNA methylation is a conserved and important epigenetic modification involved in the regulation of numerous biological processes, including plant development, secondary metabolism, and response to stresses. However, no information is available
Zhenming Yu   +8 more
doaj   +1 more source

SNP panels for the estimation of dairy breed proportion and parentage assignment in African crossbred dairy cattle

open access: yesGenetics Selection Evolution, 2021
Background Understanding the relationship between genetic admixture and phenotypic performance is crucial for the optimization of crossbreeding programs.
Netsanet Z. Gebrehiwot   +4 more
doaj   +1 more source

Histone Deacetylase HDA15 Restrains PHYB-Dependent Seed Germination via Directly Repressing GA20ox1/2 Gene Expression

open access: yesCells, 2022
Seed germination is essential for the colonization of the land plants. Light is a major environmental factor affecting seed germination, which is predominantly regulated by photoreceptor phytochrome B (PHYB). PHYB is activated by red light (designated as
Feng Zheng   +3 more
doaj   +1 more source

Inference of Ancestries and Heterozygosity Proportion and Genotype Imputation in West African Cattle Populations

open access: yesFrontiers in Genetics, 2021
Several studies have evaluated computational methods that infer the haplotypes from population genotype data in European cattle populations. However, little is known about how well they perform in African indigenous and crossbred populations.
Netsanet Z. Gebrehiwot   +6 more
doaj   +1 more source

The complete chloroplast genome of Stichorkis gibbosa (Orchidaceae: Malaxideae)

open access: yesMitochondrial DNA. Part B. Resources, 2022
Stichorkis gibbosa is a rare orchid species of the tribe Malaxideae mainly distributed in tropical Asia. This is the only species of the genus Stichorkis Thouars which has been reported to occur in China.
Wen-Ting Yang   +5 more
doaj   +1 more source

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