Results 201 to 210 of about 4,976,171 (334)

Clinical and genetic analysis of a family with myopathy caused by an FHL1 gene variant. [PDF]

BMJ Neurol Open
Zhang S, Cao X, Wu X, Huang W.
europepmc   +1 more source

Somaclonal variability of Ungernia victoris: the necessity of comprehensive genetic analysis [PDF]

, 2008
О. M. Bublyk, И. О. Андреев, Е. В. Спиридонова, В. А. Кунах   +3 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Advanced biometrical strategies for genetic analysis and heterosis assessment in maize germplasm. [PDF]

BMC Plant Biol
Jan MF, Li M, Alotaibi NM, Liaqat W, Maqbool A, Altaf MT, Arshad S, Umar A.   +7 more
europepmc   +1 more source

Genetic diversity analysis of chicken breeds of India

, 2006
M. S. Tantia, R. K. Vijh, Sanjay Kumar, Bina Mishra, Sonika Ahlawat   +4 more
openalex   +1 more source

CYP21A2mutation update: Comprehensive analysis of databases and published genetic variants

, 2017
Leandro Simonetti, Carlos David Bruque, Cecilia Fernández, Belén Benavides‐Mori, Marisol Delea, Jorge E. Kolomenski, Lucía D. Espeche, Noemí Buzzalino, Alejandro D. Nadra, Liliana Daín   +9 more
openalex   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Clinical features and genetic analysis of A20 haploinsufficiency. [PDF]

Orphanet J Rare Dis
Xue F, An C, Lei Z, Dong S, Guo Y, Hou J, Yu J, Wang Y.   +7 more
europepmc   +1 more source

Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors [PDF]

, 2005
Lars Zender, Wen Xue, Carlos Cordon‐Cardo, Gregory J. Hannon, Robert Lucito, Scott Powers, Peer Flemming, Mona S. Spector, Scott W. Lowe   +8 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source