The identification of novel missense variant in <i>ChAT</i> gene in a patient with gestational diabetes denotes plausible genetic association. [PDF]
Oluwole OG+4 more
europepmc +1 more source
Association genetic studies in grape
Association genetic methods, based on the exploitation of linkage disequilibrium (LD), are valuable tools for the dissection of complex traits. In many plant species, they indeed have shown their usefulness for the analysis of the genetic determinism of quantitative traits.
Le Cunff, Loic+20 more
openaire +2 more sources
Association of genetic variants of angiotensin-I-converting enzyme and pneumonia in elderly subjects [PDF]
Kohya Okaishi
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Genetic association analysis between LDL-c lowering drugs and portal hypertension using Mendelian randomization analysis. [PDF]
Xiao QA, Li XL, Qin L, Zhang XL.
europepmc +1 more source
Betting Odds and Genetic Associations [PDF]
David Clayton, Duncan C. Thomas
openaire +3 more sources
Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3 [PDF]
Dan Rujescu+9 more
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Genetic Association of <i>PCSK5</i> and <i>MUC2</i> Gene Polymorphisms with Recurrent Pregnancy Loss (RPL). [PDF]
Ryu CS+8 more
europepmc +1 more source
Genomic Control, a New Approach to Genetic-Based Association Studies [PDF]
Bernie Devlin+2 more
openalex +1 more source