Results 261 to 270 of about 2,718,862 (371)

Association of genetic variants of angiotensin-I-converting enzyme and pneumonia in elderly subjects [PDF]

, 2000
Kohya Okaishi
openalex   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

Molecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang, Hei Ip Hong, Victor C. Y. Mak, Yuan Zhou, Yiling Lu, Guanglei Zhuang, Lydia W. T. Cheung   +6 more
wiley   +1 more source

Genetic association between glucocorticoid receptor gene Bcl1 rs41423247 and rs6198 polymorphisms and risk of obesity in Egyptian children : By. [PDF]

Sci Rep
Salem NA, Alwakeel AA, Abdel-Latif M, Hendawy SR, Korkor MS.   +4 more
europepmc   +1 more source

Trait association of genetic markers in the growth hormone and the growth hormone receptor gene in a White Leghorn strain

, 1997
XP Feng, U. Kühnlein, Samuel E. Aggrey, J. S. Gavora, D. Zadworny   +4 more
openalex   +1 more source

Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3 [PDF]

, 2000
Dan Rujescu, Armin Szegedi, Ion Anghelescu, Ina Giegling, Anton Gietl, Martin Schäfer, F. Müller-Siecheneder, Brigitta Bondy, H.‐J. Möller, Norbert Dahmen   +9 more
openalex   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease. [PDF]

Front Endocrinol (Lausanne)
Zhang Y, Ou G, Peng L, Pan J, Zhang S, Shi J.   +5 more
europepmc   +1 more source

Computational and Experimental Analysis of Microsatellites in Rice (Oryza sativa L.): Frequency, Length Variation, Transposon Associations, and Genetic Marker Potential [PDF]

, 2001
Svetlana V. Temnykh, Genevieve DeClerck, Angelika Lukashova, Leonard Lipovich, Samuel W. Cartinhour, Susan R. McCouch   +5 more
openalex   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Association of Brain-derived Neurotrophic Factor Polymorphisms With Alcohol Use Disorder: An Updated Meta-Analysis of Genetic Association Studies. [PDF]

Brain Behav
Jenwitheesuk A, Pabalan N, Tapanadechopone P, Jarjanazi H, Arunphalungsanti K, Tharabenjasin P.   +5 more
europepmc   +1 more source