Results 261 to 270 of about 8,691,632 (395)

Association genetic studies in grape

open access: yes, 2008
Association genetic methods, based on the exploitation of linkage disequilibrium (LD), are valuable tools for the dissection of complex traits. In many plant species, they indeed have shown their usefulness for the analysis of the genetic determinism of quantitative traits.
Le Cunff, Loic   +20 more
openaire   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Betting Odds and Genetic Associations [PDF]

open access: yesJNCI Journal of the National Cancer Institute, 2004
David Clayton, Duncan C. Thomas
openaire   +3 more sources

Association study of suicidal behavior and affective disorders with a genetic polymorphism in ABCG1, a positional candidate on chromosome 21q22.3 [PDF]

open access: green, 2000
Dan Rujescu   +9 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Genetic Association of <i>PCSK5</i> and <i>MUC2</i> Gene Polymorphisms with Recurrent Pregnancy Loss (RPL). [PDF]

open access: yesInt J Mol Sci
Ryu CS   +8 more
europepmc   +1 more source

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