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Association of a genetic variant in angiopoietin-like 3 with serum HDL-C and risk of cardiovascular disease: A study of the MASHAD cohort over 6 years

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M Aghasizadeh (21298901)   +12 more
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Genetic association studies

The Lancet, 2005
We review the rationale behind and discuss methods of design and analysis of genetic association studies. There are similarities between genetic association studies and classic epidemiological studies of environmental risk factors but there are also issues that are specific to studies of genetic risk factors such as the use of particular family-based ...
Cordell HJ, Clayton DG
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Genetic associates/counselors in genetic services

American Journal of Medical Genetics, 1980
AbstractA survey of US directors of genetic services showed that about 38% of the non‐physician professionals providing such services are genetic associates/counselors (GAs). Over 90% of GAs appear to be involved in direct human services, rather than in the performance of laboratory procedures or research.Although they wanted GAs to be competent in ...
Seymour Kessler, John M. Optiz
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Spurious Genetic Associations

Biological Psychiatry, 2007
Genetic association studies are widely used in biomedical research and yet only a minority of positive findings stand the test of replication. I explored the capacity of association studies to produce false positive findings and the impact of various definitions of replication.Genetically realistic simulation data of a typical genotyping/analytic ...
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Genetic Variations and Association

2010
Publisher Summary This chapter provides information about the human hydroxytryptamine (HT)R6 gene structure, its evolution, and its expression profile in both the brain and in peripheral tissues. The chapter describes the regulatory regions like binding sites for transcription factors (TFs) or for miRNA.
GENNARELLI, Massimo, CATTANEO, Annamaria
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