Results 331 to 340 of about 2,718,862 (371)

Decoding multicellular interaction networks–a new horizon in tumor microenvironment research

Molecular Oncology, Volume 19, Issue 4, Page 957-960, April 2025.
Cells in the tumor microenvironment influence tumor establishment and progression through an elaborate array of cellular interactions. Integrating transcriptomic, spatial, and intercellular crosstalk data at single‐cell resolution unveil complex, functionally distinct multicellular circuits.
Roi Balaban, Merav Cohen
wiley   +1 more source

Genetic association of type 2 diabetes mellitus and glycaemic factors with primary tumours of the central nervous system. [PDF]

BMC Neurol
Li Y, Lin L, Zhang W, Wang Y, Guan Y.
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Maximal Fat Oxidation During Exercise in Healthy Individuals: Lack of Genetic Association with the <i>FTO</i> rs9939609 Polymorphism. [PDF]

Genes (Basel)
García-Pastor T, Muñoz-Puente I, Pérez-Pelayo M, Púa I, Roberts JD, Del Coso J.   +5 more
europepmc   +1 more source

Genetic association of antinuclear antibodies with HLA in JIA patients: a Swedish cohort study. [PDF]

Pediatr Rheumatol Online J
Saleh R, Sundberg E, Olsson M, Tengvall K, Alfredsson L, Kockum I, Padyukov L, Harris HE.   +7 more
europepmc   +1 more source

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Genetic association studies

The Lancet, 2005
We review the rationale behind and discuss methods of design and analysis of genetic association studies. There are similarities between genetic association studies and classic epidemiological studies of environmental risk factors but there are also issues that are specific to studies of genetic risk factors such as the use of particular family-based ...
Cordell HJ, Clayton DG
openaire   +3 more sources

Genetic associates/counselors in genetic services

American Journal of Medical Genetics, 1980
AbstractA survey of US directors of genetic services showed that about 38% of the non‐physician professionals providing such services are genetic associates/counselors (GAs). Over 90% of GAs appear to be involved in direct human services, rather than in the performance of laboratory procedures or research.Although they wanted GAs to be competent in ...
John M. Optiz, Seymour Kessler
openaire   +3 more sources

Genetic Variations and Association

2010
Publisher Summary This chapter provides information about the human hydroxytryptamine (HT)R6 gene structure, its evolution, and its expression profile in both the brain and in peripheral tissues. The chapter describes the regulatory regions like binding sites for transcription factors (TFs) or for miRNA.
GENNARELLI, Massimo, CATTANEO, Annamaria
openaire   +4 more sources

Genetics of microtia and associated syndromes

Journal of Medical Genetics, 2009
Microtia is a congenital anomaly, characterised by a small, abnormally shaped auricle (pinna). It is usually accompanied by a narrow, blocked or absent ear canal. Microtia can occur as the only clinical abnormality or as part of a syndrome. The estimated prevalence of microtia is 0.8-4.2 per 10 000 births, and it is more common in men.
Alasti, F., Van Camp, Guy
openaire   +4 more sources

Spurious Genetic Associations

Biological Psychiatry, 2007
Genetic association studies are widely used in biomedical research and yet only a minority of positive findings stand the test of replication. I explored the capacity of association studies to produce false positive findings and the impact of various definitions of replication.Genetically realistic simulation data of a typical genotyping/analytic ...
openaire   +2 more sources