The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Genetic association analysis of lipid-lowering drug target genes in chronic kidney disease. [PDF]
Zhang Y +5 more
europepmc +1 more source
Absence of genetic association between insulin-like growth factors and esophageal cancer. [PDF]
Sun Z, Wang X.
europepmc +1 more source
Leptin promoter G2548A variant, elevated plasma leptin levels, and increased risk of Type 2 diabetes with CAD in Iranian patients: A genetic association study. [PDF]
Saremi L +5 more
europepmc +1 more source
Unraveling the genetic association between knee osteoarthritis and hallux deformities. [PDF]
Lv Z +7 more
europepmc +1 more source
Genetic association of lipid-lowering drug target genes with pancreatic cancer: a Mendelian randomization study. [PDF]
Su B, Fan Z, Wu J, Zhan H.
europepmc +1 more source
Genetic association of type 2 diabetes and antidiabetic drug target with skin cancer. [PDF]
Zhao J, Zhang Y, Li J, Li Q, Teng Z.
europepmc +1 more source
Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease.
Fan J +14 more
europepmc +1 more source

