Results 261 to 270 of about 2,429,135 (273)
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Genetic Markers: Association Study in Migraine
Cephalalgia, 1995Eleven genetic markers were typed in 112 unrelated patients with migraine (50 with aura, 62 without aura) and compared with a random sample of healthy individuals. No significant differences were found for the ABO and Rh systems, acid phosphatase 1, phosphoglucomutase 1, adenosine deaminase, haptoglobin, transferrin, alpha-1–antitrypsin, and D1S80 ...
J, Pardo +5 more
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Genetic Association Studies in Diabetic Nephropathy
Current Diabetes Reviews, 2012Clinical observations and epidemiological studies have shown that there is familial aggregation of diabetic nephropathy in many ethnic groups, indicating the strong contribution of inherited factors in the development of diabetic nephropathy. Identification of the genes involved in the pathogenesis of diabetic nephropathy may provide better knowledge ...
Harvest F, Gu, Kerstin, Brismar
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2016
Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide ...
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Genetic Association Studies is designed for students of public health, epidemiology, and the health sciences, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide ...
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Association Studies in Genetics
2011This chapter is devoted at first to a quick review of case control studies in genetic epidemiology. The case–control method is usually applied in genetic epidemiology to elucidate the role of genetic factors and their interaction with environmental factors in the aetiology of human diseases.
Luigi Salmaso +3 more
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Detecting Sample Misidentifications in Genetic Association Studies
Statistical Applications in Genetics and Molecular Biology, 2012Genetic association studies require that the genotype data from a given person can be correctly linked to the phenotype data from the same person. However, sample misidentification errors sometimes happen, whereby the link becomes invalid for some of the subjects in a study.
Ekstrøm, Claus Thorn, Feenstra, B
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Methodological issues of genetic association studies
Clinical Chemistry and Laboratory Medicine, 2010Genetic association studies explore the association between genetic polymorphisms and a certain trait, disease or predisposition to disease. It has long been acknowledged that many genetic association studies fail to replicate their initial positive findings. This raises concern about the methodological quality of these reports.
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Genetic association studies in β-hemoglobinopathies
Hematology, 2013AbstractCharacterization of the molecular basis of the β-thalassemias and sickle cell disease (SCD) clearly showed that individuals with the same β-globin genotypes can have extremely diverse clinical severity. Two key modifiers, an innate ability to produce fetal hemoglobin and coinheritance of α-thalassemia, both derived from family and population ...
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