Results 151 to 160 of about 2,571,979 (334)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Distribution and genetic characterization of fluoroquinolone resistance gene qnr among Salmonella strains from chicken in China

open access: yesMicrobiology Spectrum
The prevalence and dissemination of the plasmid-mediated fluoroquinolone (FQ) resistance gene qnr in Salmonella are considered serious public health concerns worldwide.
Yang Chen   +9 more
doaj   +1 more source

Clinicopathological and Genetic Characteristics of Patients of Different Ages with Diffuse Sclerosing Variant Papillary Thyroid Carcinoma [PDF]

open access: gold, 2023
Soo Young Kim   +8 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A Genetic Algorithm with Design of Experiments Approach to Predict the Optimal Process Parameters for FDM [PDF]

open access: yes, 2005
This paper describes a Genetic Algorithm (GA) with Design of Experiments (DoE) approach to predict the optimized surface roughness and porosity characteristics of the parts produced using ABS material on stratasys FDM 2000 machine.
Arumaikkannu, G.   +2 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Diffusion of Development [PDF]

open access: yes
This paper studies the barriers to the diffusion of development across countries from a longterm perspective. We find that genetic distance, a measure associated with the amount of time elapsed since two populations’ last common ancestors, bears a ...
Enrico Spolaore, Romain Wacziarg
core  

Genomic epidemiology and characterization of Staphylococcus aureus isolates from raw milk in Jilin, China: evidence of contamination with optrA-positive, cfrA-positive, and poxtA-positive strains and human–livestock transmission

open access: yesFrontiers in Microbiology
Jilin province is the primary region for dairy cow and milk production in China. However, there are few reports on the genetic characteristics, antibiotic resistance, and prevalence of Staphylococcus aureus (S. aureus) in raw milk. Between 2021 and 2022,
Qianhong Liu   +5 more
doaj   +1 more source

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