Results 221 to 230 of about 2,571,979 (334)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Genetic characteristics and epidemiology of influenza and respiratory syncytial viruses associated with acute respiratory infections in Thailand. [PDF]

BMC Infect Dis
Kamolvathin N, Mangmee S, Phuphanitcharoenkun S, Kamchompoo N, Suthisawat S, Kosoltanapiwat N, Tongshoob J, Huntrup A, Mansanguan C, Boonnak K.   +9 more
europepmc   +1 more source

Genetic Diversity of Kedu Chicken Based on Phenotypic Characteristics and Microsatellite Loci [PDF]

, 2012
Ismoyowati Ismoyowati, Sukardi Sukardi, Agus Susanto   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The Analysis of Morphological and Genetic Characteristics of Yellowstripe Scad from Muara Baru Modern Fish Market in North Jakarta

, 2020
Rahmat Sawalman, Hawis Madduppa
openalex   +2 more sources

Relation Between Serum Cholesterol Level, Lipoprotein Concentration and Carcass Characteristics in Genetically Lean and Fat Chicken Breeds [PDF]

, 2006
Hassan Hussein Musa, G.H. Chen ., K.H. Wang ., B.C. Li ., D.M. Mekki ., Jianbo Shu, Hyun Park Ju   +6 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Molecular Detection and Genetic Characteristics of Equine Herpesviruses 1 and 4 in Egypt. [PDF]

Vet Med Int
Al-Ebshahy E, Badr Y, El-Ansary RE, Alajmi R, El-Ashram S, Rady A, Elgendy E.   +6 more
europepmc   +1 more source

Identification of biological characteristics and preliminary research on genetic transformation of the Aspergillus niger TL8 strain isolated in Vietnam

, 2017
Do Thi Binh Xuan Loc, Van‐Tuan Tran
openalex   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source