Results 31 to 40 of about 2,305,947 (261)

Genetic diversity and core subset selection in ex situ seed collections of the banana crop wild relative Musa balbisiana [PDF]

, 2019
Crop wild relatives (CWRs) play a key role in crop breeding by providing beneficial trait characteristics for improvement of related crops. CWRs are more efficiently used in breeding if the plant material is genetically characterized, but the diversity ...
Bawin, Yves, Ge, Xue-Jun, Honnay, Olivier, Janssens, Steven, Li, Zhiying, Mertens, Arne, Panis, Bart, Poafa, Janet, Sardos, July, Vanden Abeele, Samuel   +9 more
core   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]

, 2018
Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Unique features of Plasmids among different Citrobacter species [PDF]

, 2012
The _Citrobacter_ plasmids are supposed to represent the host genetic association within the living bacterial cell. The plasmids impart various beneficial characteristics to the host, helping it to retain suitable characteristics for adaptation as well ...
Swapnil G. Sanmukh, Waman N. Paunikar
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

On the Breeds of Cattle—Historic and Current Classifications [PDF]

, 2011
Classification of cattle breeds contributes to our understanding of the history of cattle and is essential for an effective conservation of genetic diversity.
Adametz, Adametz, Ajmone-Marsan, Alderson, Alderson, Aparicio, Auld, Baker, Baron, Bisschop, Bojanus, Bougler, Bradley, Bruford, Chacrin, Cheng, Clason, Curson, Cymbron, De Buffon, Dechambre, Decker, Denis, Denis, Diffloth, Doutresoulle, Duerst, Duerst, Dürst, Epstein, Epstein, Epstein, Falconer, Felius, Felius, Fernández, Fitzinger, Freeman, French, Groeneveld, Grosclaude, Hanotte, Hansen, Haring, Hengeveld, Hilzheimer, Hodges, Holecek Holleschowitz, Joshi, Joshi, Kaltenegger, Keller, Knowles, Kroes, Kronacher, Laloë, Lamarck, Leithner, Lenstra, Magerstedt, Martin-Burriel, Martin-Burriel, Mason, Mason, Maule, Maule, McKenny Hughes, Miranda do Vale, Mommens, Müller, Negrini, Nilsson, Olver, Payne, Payne, Ramm, Rath, Rege, Rütimeyer, Sanchez Belda, Sanchez Belda, Sanson, Simon, Thaer, Troy, Vallejo, Von Nathusius, Werner, Wilckens, Wilson, Youatt, Zeuner, Zwaenepoel   +92 more
core   +2 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source