Results 221 to 230 of about 209,232 (313)

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

[Book Review of] \u3cem\u3eGenetic Counseling: Facts, Values, and Norms,\u3c/em\u3e edited by Alexander M. Capron et al. [PDF]

, 1981
Green, Michael
core   +1 more source

P617: Utility of negative fetal exome sequencing in diagnosing chondrodysplasia punctata associated with maternal systemic lupus erythematosus: A case report

Genetics in Medicine Open, 2023
Christina Miller, Kestutis Micke
doaj  

Experiences of having an eating disorder and perceptions of its etiology: A qualitative study to inform genetic counseling practice. [PDF]

J Genet Couns
Wang C, Slomp C, Austin JJ.
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Call to action for genetic counseling research in hereditary cancer: Considerations from the evidence-based guidelines development process. [PDF]

J Genet Couns
Levin B, Salo-Mullen E, Culver JO, Kurz RN, Brock P, Demsky R, Lloyd S, Lopez G, Mai PL, Wolfe Schneider K.   +9 more
europepmc   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Terminal deletion of 11q in two brothers: Clinical, cytogenetic, molecular genetic and counseling issues

, 2000
Mary Haag, S M Phillips, M.L. Tubby, Linda Beischel, Cathleen McCann, J.P. Johnson, James F. Reynolds, Jeffrey C. Hansen   +7 more
openalex   +1 more source

Case Report: The importance of genetic counseling for families with hyperinsulinism. [PDF]

Front Pediatr
Sanders VR, Lord K, Sigal WM, McKnight H, Adzick NS, States LJ, Bhatti T, De Leon DD.   +7 more
europepmc   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source