Results 41 to 50 of about 544,097 (312)

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Prevalence and risk factors for vitamin C deficiency in North and South India: A two centre population based study in people aged 60 years and over [PDF]

, 2011
BackgroundStudies from the UK and North America have reported vitamin C deficiency in around 1 in 5 men and 1 in 9 women in low income groups. There are few data on vitamin C deficiency in resource poor countries.ObjectivesTo investigate the prevalence ...
K. Gupta Sanjeev, Maraini Giovanni, Ravilla D. Ravindran, Giovanni Maraini, Ravilla Thulasiraj D., John Neena, Thulasiraj D. Ravilla, John, Neena, Thulasiraj D Ravilla, Young, Ian S., R Jayanthi, S. Young Ian, Usha Chakravarthy, Chakravarthy Usha, Fletcher Astrid E., Young, Ian S, Ravilla D Ravindran, Praveen Vashist, Ravilla, Thulasiraj D, Chakravarthy, Usha, Kathryn E. Fitzpatrick, Fitzpatrick, Kathryn E, Camparini, Monica, Astrid E Fletcher, Gupta, S.K., R. Jayanthi, Maraini, G., John, N., Ravilla, T.D., Fitzpatrick Kathryn E., Fitzpatrick, K.E., Maraini, Giovanni, Camparini, M., Fletcher, Astrid E, Gupta, Sanjeev K, Monica Camparini, Kathryn E Fitzpatrick, Ravindran, Ravilla D, Neena John, Fletcher, A.E., Jayanthi, R, Sanjeev K Gupta, Ravindran, R.D., Vashist Praveen, Sanjeev K. Gupta, Vashist, Praveen, Astrid E. Fletcher, Camparini Monica, Ian S Young, Jayanthi R., Jayanthi, R., Ravindran Ravilla D., Vashist, P., Ian S. Young   +53 more
core   +1 more source

Genetic Therapy Approaches for Ornithine Transcarbamylase Deficiency

Biomedicines, 2023
Ornithine transcarbamylase deficiency (OTCD) is the most common urea cycle disorder with high unmet needs, as current dietary and medical treatments may not be sufficient to prevent hyperammonemic episodes, which can cause death or neurological sequelae.
Berna Seker Yilmaz, Paul Gissen
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Genetic regulation of pituitary gland development in human and mouse

, 2009
Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke’s ...
Robin Lovell-Badge, Dattani, M. T., Robinson, I. C. A. F., Mehul T. Dattani, Lovell-Badge, R., Karine Rizzoti, Iain C. A. F. Robinson, Rizzoti, K., Kelberman, D., Daniel Kelberman   +9 more
core   +1 more source

Candidate polymorphisms and severe malaria in a Malian population. [PDF]

, 2012
Malaria is a major health burden in sub-Saharan African countries, including Mali. The disease is complex, with multiple genetic determinants influencing the observed variation in response to infection, progression, and severity.
Belco Poudiougou, Toure, Ousmane, Sall, Abdourahmane H, Kirk A Rockett, Ogobara Doumbo, Sissoko Sibiri, Diarra Elisabeth, Amadou Niangaly, Konate Salimata, Barry, Abdoulaye, Taane G Clark, Taane G. Clark (106263), Sibiri Sissoko, Poudiougou Belco, Sall Abdourahmane H., Thera, Mahamadou A, Ousmane Toure (22538), Collaboration with The MalariaGEN Consortium, Mahamadou A Thera, Abdourahmane H Sall, Nuno Sepulveda, Poudiougou, Belco, Clark, Taane G, Sibiri Sissoko (138104), Thera Mahamadou A., Elisabeth Diarra (138119), Salimata Konate (138100), Campino Susana, Doumbo Ogobara, Diarra, Elisabeth, Nuno Sepulveda (124822), Ousmane Toure, Susana Campino, Kirk A. Rockett (138127), Rockett, Kirk A, Abdourahmane H. Sall (138114), Toure Ousmane, Amadou Niangaly (83858), Ogobara Doumbo (35290), Barry Abdoulaye, Campino, Susana, Susana Campino (56411), Rockett Kirk A., Abdoulaye Barry (138109), Clark Taane G., Sepulveda, Nuno, Elisabeth Diarra, Konate, Salimata, Abdoulaye Barry, Belco Poudiougou (22535), Mahamadou A. Thera (35284), Sepulveda Nuno, Niangaly, Amadou, Salimata Konate, Niangaly Amadou, Sissoko, Sibiri, Doumbo, Ogobara   +56 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Thrombosis in inherited factor VII deficiency

, 2003
Thrombosis in congenital factor (F) VII deficiency was investigated through extensive phenotypic and molecular-genetic studies. Patients with a history of thrombosis among 514 entries in the FVII Deficiency Study Group database were evaluated. Thrombotic
WULFF K, DOLCE A, AUERSWALD G, ASTERMARK J, BERNARDI, Francesco, INTERNATIONAL FACTOR VII DEFICIENCY STUDY GROUP, BATOROVA A, HERRMANN FH, MARIANI G, SCHVED JF, SCHULMAN S, INGERSLEV J, ETRO, Daniela   +12 more
core   +1 more source