Results 151 to 160 of about 2,140,335 (329)

TRPM4 contributes to cell death in prostate cancer tumor spheroids, and to extravasation and metastasis in a zebrafish xenograft model system

Molecular Oncology, EarlyView.
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen, Saurav Subedi, Federico La Manna, Sofia Jarrin, Irida Papapostolou, Marianna Kruithof‐de Julio, Christine Peinelt   +6 more
wiley   +1 more source

STUDIES ON THE BREEDING OF RICE VARIETIES RESISTANT TO STRIPE DISEASE : II. Genetic Study on Resistance to Stripe Disease in Japanese Upland Rice

, 1968
Osamu Washio, Kunio Toriyama, Akinori EZUKA, Y. Sakurai   +3 more
openalex   +2 more sources

Gene Therapy for Human Genetic Disease? [PDF]

, 1972
Elizabeth F. Neufeld, Charles C. Sweeley
openalex   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Editorial: Noncanonical functions of Aminoacyl-tRNA synthetases

Frontiers in Physiology, 2023
Litao Sun, Xiao-Long Zhou, Zhong-Wei Zhou, Haissi Cui   +3 more
doaj   +1 more source

« À mains raccourcies » ou l’histoire de l’hémochromatose

UISPP Journal
L’auteur se propose ici de faire le point sur l’histoire de l’hémochromatose, l’une des plus importantes maladies d’origine génétique actuelles. A partir d’exemples récents et de l’étude de deux cas personnels, l’analyse historique de l’hémochromatose ...
Jean Zammit
doaj   +1 more source

RNA therapy is shining for genetic diseases. [PDF]

Mol Ther Nucleic Acids, 2023
Zheng ZM.
europepmc   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Selected Screening Tests for Genetic Metabolic Diseases [PDF]

, 1975
D. N. Raine
openalex   +1 more source

Advance in Genomics of Rare Genetic Diseases. [PDF]

Biomolecules, 2023
Sommariva E, Bellin M, Di Resta C.
europepmc   +1 more source