Results 151 to 160 of about 13,191,301 (426)

Mosquito Innate Immunity

Insects, 2018
Mosquitoes live under the endless threat of infections from different kinds of pathogens such as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical and physiological barriers that resist the entry of the pathogen and
Ankit Kumar, Priyanshu Srivastava, PDNN Sirisena, Sunil Kumar Dubey, Ramesh Kumar, Jatin Shrinet, Sujatha Sunil   +6 more
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Principles of Periodontology [PDF]

, 2013
Periodontal diseases are among the most common diseases affecting humans. Dental biofilm is a contributor to the etiology of most periodontal diseases.
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core   +2 more sources

Establishment and Comparison of Pathogenicity and Related Neurotropism in Two Age Groups of Immune Competent Mice, C57BL/6J Using an Indian Isolate of Chikungunya Virus (CHIKV)

Viruses, 2019
Chikungunya (CHIK) is a febrile arboviral illness caused by chikungunya virus (CHIKV) and has been identified in more than 60 countries across the globe.
Jaspreet Jain, Vimal Narayanan, Ankit Kumar, Jatin Shrinet, Priyanshu Srivastava, Shivam Chaturvedi, Sujatha Sunil   +6 more
doaj   +1 more source

Disentangling genetic and environmental risk factors for individual diseases from multiplex comorbidity networks [PDF]

arXiv, 2016
Most disorders are caused by a combination of multiple genetic and/or environmental factors. If two diseases are caused by the same molecular mechanism, they tend to co-occur in patients. Here we provide a quantitative method to disentangle how much genetic or environmental risk factors contribute to the pathogenesis of 358 individual diseases ...
arxiv  

CRISPR/Cas9 in zebrafish: an efficient combination for human genetic diseases modeling

Human Genetics, 2016
The next-generation sequencing identifies a growing number of candidate genes associated with human genetic diseases, which inevitably requires efficient methods to validate the causal links between genotype and phenotype.
Jiaqi Liu, Yangzhong Zhou, Xiaolong Qi, Jia Chen, Weisheng Chen, G. Qiu, Zhihong Wu, N. Wu   +7 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Analysis of DTC nutrigenetic services in Italy: state of the art, agreement to the ESHG statement and future outlooks [PDF]

, 2012
Background: In both USA and Europe operate companies selling Direct-to-consumer genetic tests (DTC). These tests are offered to healthy people aiming to identify predispositions to complex diseases and to take preventive measures.
Alessandra Cianflone, Antonella Monticelli, Fabio Acquaviva, Imma Castaldo, Michele Pinelli, Paola Vergara, Sergio Cocozza, Vincenzo Cinque   +7 more
core   +1 more source

The genetics of neurodevelopmental disease [PDF]

Current Opinion in Neurobiology, 2011
The term neurodevelopmental disorder encompasses a wide range of diseases, including recognizably distinct syndromes known to be caused by very rare mutations in specific genes or chromosomal loci, and also much more common disorders such as schizophrenia, autism spectrum disorders, and idiopathic epilepsy and mental retardation.
openaire   +5 more sources

CRISPR/Cas9 therapeutics: a cure for cancer and other genetic diseases

OncoTarget, 2016
Cancer is caused by a series of alterations in genome and epigenome mostly resulting in activation of oncogenes or inactivation of cancer suppressor genes.
F. A. Khan, N. Pandupuspitasari, Chunjie Huang, Zhou Ao, M. Jamal, A. Zohaib, F. A. Khan, Muthia Raihana Hakim, Shujun Zhang   +8 more
semanticscholar   +1 more source