Results 191 to 200 of about 1,395,753 (295)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Next-generation sequencing (NGS) techniques for pre-symptomatic identification of genetic diseases in newborns. [PDF]

Cochrane Database Syst Rev
Pessano S, Boldor M, Faravelli F, Fiander M, Jørgensen KJ, Soll RF, Bruschettini M.   +6 more
europepmc   +1 more source

The Risk of Transmission of Genetic Prion Diseases is Greater Than 50% [PDF]

Izaro Kortazar‐Zubizarreta, África Manero-Azua, Hasier Eraña, Urko Aguire, Joaquı́n Castilla, Guiomar Pérez de Nanclares   +5 more
openalex   +1 more source

RETRACTED: Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer’s Disease [PDF]

, 2018
Jessie S. Carr, Luke W. Bonham, Alicia K. Morgans, Charles J. Ryan, Jennifer S. Yokoyama, Ethan G. Geier, Alzheimer’s Disease Neuroimaging Initiative   +6 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Author Correction: Between hope and reality: treatment of genetic diseases through nucleic acid-based drugs. [PDF]

Commun Biol
Baylot V, Le TK, Taïeb D, Rocchi P, Colleaux L.   +4 more
europepmc   +1 more source

Inheritance of Genetic variability, Combining Ability and Heterosis for Yellow Mosaic Virus Disease Resistance and Yield Improvement in Blackgram [Vigna mungo (L.) Hepper] [PDF]

, 2017
R. Suguna, P. Savitha, C.R. Ananda Kumar
openalex   +1 more source

Genetics in cardiovascular disease

Heart Views, 2020
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Editorial: The clinical utility of long read sequencing to improve diagnostic yield and uncover biological mechanisms in rare disease

Frontiers in Genetics
Lidia Larizza, Christopher M. Watson, Christopher M. Watson, Madelyn A. Gillentine, Palma Finelli, Palma Finelli   +5 more
doaj   +1 more source