Results 201 to 210 of about 2,140,385 (376)

Problem-based Learning in an Online Course: A case study

open access: yesInternational Review of Research in Open and Distributed Learning, 2005
Problem-based learning (PBL) is the use of a “real world” problem or situation as a context for learning. The present study explores the use of PBL in an online biotechnology course.
James Cheaney, Thomas S. Ingebritsen
doaj  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Genetic Counselling in X-Linked Eye Diseases [PDF]

open access: bronze, 1973
J. François   +3 more
openalex   +1 more source

Human hepatic organoids for the analysis of human genetic diseases. [PDF]

open access: yesJCI Insight, 2023
Guan Y   +11 more
europepmc   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Temperature-sensitive Mutants of Foot-and-Mouth Disease Virus: the Isolation of Mutants and Observations on their Properties and Genetic Recombination

open access: bronze, 1975
J. S. Mackenzie   +6 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Diagnóstico y prevención de enfermedades genéticas. Análisis de seis años del municipio Sandino Diagnostic and prevention of the genetic diseases. Analysis of six years of the municipality Sandino

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2008
Introducción: En los últimos años ha aumentado la importancia de las anomalías congénitas y enfermedades hereditarias como causa de muerte en el primer año de vida.
Pedro Antonio Ramírez Sosa   +3 more
doaj  

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