Results 241 to 250 of about 12,192,107 (344)
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome project. [PDF]
Lam WKJ+38 more
europepmc +1 more source
Genetic Diseases of Mucopolysaccharide Catabolism; Single-Enzyme Deficiency Disorders
Elizabeth F. Neufeld
openalex +2 more sources
Genetic Eye Disease: Retinitis Pigmentosa and Other Inherited Eye Diseases [PDF]
B. Jay
openalex +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Oral Problems in Brazilian Individuals with Rare Genetic Diseases That Affect Skeletal Development. [PDF]
Rabello F+6 more
europepmc +1 more source
Interactive influence of infectious disease and genetic diversity in natural populations
Stephen J. O’Brien, James F. Evermann
openalex +1 more source
URIDINE MONOPHOSPHATE KINASE (UMPK)-A NEW GENETIC MARKER FOR SUSCEPTIBILITY TO HAEMOPHILUS INFLUENZAE TYPE B (HIB) DISEASE [PDF]
Gloria M. Petersen+5 more
openalex +1 more source