Results 121 to 130 of about 3,343,818 (361)

GABAA receptors in epilepsy: Elucidating phenotypic divergence through functional analysis of genetic variants [PDF]

open access: hybrid, 2023
Nathan L. Absalom   +6 more
openalex   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Genetic divergence analysis of lime

open access: yesJournal of the Bangladesh Agricultural University, 1970
Genetic divergence of 40 lime accessions was estimated using D2 and principal component analysis. The genotypes under study fell into 6 clusters. The distribution pattern indicated that the maximum number of genotypes were included in cluster III and the minimum number in cluster VI.
MM Rahman, MAZ Al Munsur
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

DIVERGÊNCIA GENÉTICA NUMA POPULAÇÃO F5 DE MELÃO

open access: yesRevista Caatinga, 2008
The aim of this paper was to evaluate the genetic divergence of a melon population of the Plant Breeding Program from the Federal University of Alagoas.
Marcelo Cavalcante   +4 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genetic diversity in wild stocks of the giant freshwater prawn (Macrobrachium rosenbergii): implications for aquaculture and conservation [PDF]

open access: yes
The giant freshwater prawn (Macrobrachium rosenbergii) is cultured widely around the world but little is known about the levels and patterns of genetic diversity in either wild or cultured stocks.
de Bruyn, M., Mather, P.B.
core  

Home - About - Disclaimer - Privacy