Results 261 to 270 of about 5,420,865 (302)
Some of the next articles are maybe not open access.
New England Journal of Medicine, 2005
The process of transformation of normal melanocytes into malignant melanoma requires the acquisition of genomic abnormalities. Dr. Paul Meltzer writes that tracking down the genetic changes in cancer has proved to be a powerful approach to the selection of therapeutic targets.
openaire +3 more sources
The process of transformation of normal melanocytes into malignant melanoma requires the acquisition of genomic abnormalities. Dr. Paul Meltzer writes that tracking down the genetic changes in cancer has proved to be a powerful approach to the selection of therapeutic targets.
openaire +3 more sources
Genetic Diversity in Hemoglobins
JAMA: The Journal of the American Medical Association, 1978To the Editor.— In their excellent discussion of "Genetic Diversity in Hemoglobins: Disease and Nondisease" (239:2681, 1978), Scott and Gilbert comment on the gene prevalence for several common autosomal recessive hematologic and nonhematologic disorders.
openaire +3 more sources
The American Journal of Bioethics, 2015
The idea that a world in which everyone was born "perfect" would be a world in which something valuable was missing often comes up in debates about the ethics of technologies of prenatal testing and preimplantation genetic diagnosis (PGD). This thought plays an important role in the "disability critique" of prenatal testing.
openaire +3 more sources
The idea that a world in which everyone was born "perfect" would be a world in which something valuable was missing often comes up in debates about the ethics of technologies of prenatal testing and preimplantation genetic diagnosis (PGD). This thought plays an important role in the "disability critique" of prenatal testing.
openaire +3 more sources
Science, 1998
Elizabeth Pennisi, in her News & Comment article about a new National Research Council (NRC) report “Evaluating human genetic diversity” (24 Oct. p. [568][1]), states that the committee (which I chaired) that wrote the report gave “a cautious nod of approval” to a proposed global survey of human genetic diversity. The committee strongly endorses such a
openaire +3 more sources
Elizabeth Pennisi, in her News & Comment article about a new National Research Council (NRC) report “Evaluating human genetic diversity” (24 Oct. p. [568][1]), states that the committee (which I chaired) that wrote the report gave “a cautious nod of approval” to a proposed global survey of human genetic diversity. The committee strongly endorses such a
openaire +3 more sources
The Genetics of Chemical Diversity
Critical Reviews in Microbiology, 1994The plethora of natural organic chemicals contrasts with the relative scarcity of genes and the apparent difficulty to evolve new ones. The genetical analysis of metabolism may be reviewed with this paradox in mind. The terpenoids constitute a particularly varied group of natural compounds; many of them are dispensable to the cell and their ...
openaire +3 more sources
Genetic diversity in the Caucasus.
Human biology, 1994We report genetic variation in the Caucasus, a region showing extreme linguistic differentiation. Spatial autocorrelation analysis of 31 alleles in 793 samples and maps of interpolated allele frequencies show significant geographic structure, but the patterns are clinical for only a few alleles. Many gene frequency distributions are patchy, most likely
BARBUJANI, Guido +2 more
openaire +2 more sources
Maintaining the Diversity of Genetic Programs
2002The loss of genetic diversity in evolutionary algorithms may lead to suboptimal solutions. Many techniques have been developed for maintaining diversity in genetic algorithms, but few investigations have been done for genetic programs. We define here a diversity measure for genetic programs based on our metric for genetic trees [3].
Sandor Nemeth, Anikó Ekárt
openaire +2 more sources
Genetic Diversity in Mycobacterium tuberculosis
2013Recent years have witnessed an increased appreciation of the extent and relevance of strain-to-strain variation in Mycobacterium tuberculosis. This paradigm shift can largely be attributed to an improved understanding of the global population structure of this organism, and to the realisation that the various members of the M.
openaire +3 more sources