Results 151 to 160 of about 82,403 (248)

Harvest and decimation affect genetic drift and the effective population size in wild reindeer. [PDF]

Evol Appl
Kvalnes T, Flagstad Ø, Våge J, Strand O, Viljugrein H, Sæther BE.   +5 more
europepmc   +1 more source

Correction to: Genetic Drift Shapes the Evolution of a Highly Dynamic Metapopulation. [PDF]

Mol Biol Evol, 2023
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic drift promotes and recombination hinders speciation on holey fitness landscapes. [PDF]

PLoS Genet
Kalirad A, Burch CL, Azevedo RBR.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans. [PDF]

Elife
Bénitière F, Necsulea A, Duret L.
europepmc   +1 more source

Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection. [PDF]

Mol Biol Evol, 2021
Armstrong EE, Khan A, Taylor RW, Gouy A, Greenbaum G, Thiéry A, Kang JT, Redondo SA, Prost S, Barsh G, Kaelin C, Phalke S, Chugani A, Gilbert M, Miquelle D, Zachariah A, Borthakur U, Reddy A, Louis E, Ryder OA, Jhala YV, Petrov D, Excoffier L, Hadly E, Ramakrishnan U.   +24 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A new lysine biosynthetic enzyme from a bacterial endosymbiont shaped by genetic drift and genome reduction. [PDF]

Protein Sci
Gilkes JM, Frampton RA, Board AJ, Hudson AO, Price TG, Morris VK, Crittenden DL, Muscroft-Taylor AC, Sheen CR, Smith GR, Dobson RCJ.   +10 more
europepmc   +1 more source

Population differences in Chinook salmon (Oncorhynchus tshawytscha) DNA methylation: Genetic drift and environmental factors. [PDF]

Ecol Evol, 2021
Venney CJ, Sutherland BJG, Beacham TD, Heath DD.   +3 more
europepmc   +1 more source