Results 231 to 240 of about 5,695,316 (423)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Determination of residue specificity in the EF-hand of troponin C for Ca2+ coordination, by genetic engineering.

, 1992
A. Babu, Hang Su, Yeong Ryu, J. Gulati
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

God players: Genetic engineering

Contemporary Clinical Dentistry, 2010
S G Damle
doaj  

Engineering drought and salt tolerance in plants using SodERF3, a novel sugarcane ethylene responsive factor

Biotecnología Aplicada
The ability of plants to tolerate salt and drought conditions is crucial for agricultural production worldwide. The increased understanding of the regulatory networks controlling drought stress response has led to practical approaches for engineering ...
Luis E Trujillo, Carmen Menéndez, María E Ochogavía, Ingrid Hernández, Orlando Borrás, Raisa Rodríguez, Yamilet Coll, Juan G Arrieta, Alexander Banguela, Ricardo Ramírez, Lázaro Hernández   +10 more
doaj  

Advancements in Crop PUFAs Biosynthesis and Genetic Engineering: A Systematic and Mixed Review System. [PDF]

Int J Mol Sci
Assefa M, Zhao Y, Zhou C, Song Y, Zhao X.   +4 more
europepmc   +1 more source

Resent study for genetic engineering of soybean glycinin gene.

, 1990
Takayuki Momma
openalex   +1 more source

INGENIERÍA GENÉTICA E INDUSTRIA AGROALIMENTARIA: VENTAJAS E INCONVENIENTES GENETIC ENGINEERING AND FOOD INDUSTRY: ADVANTAGES AND INCONVENIENCES EXEÑERÍA XENÉTICA E INDUSTRIA AGROALIMENTARIA: VENTAXAS EINCONVINTES [PDF]

, 1999
Roberto Rodríguez Madrera, Yolanda Picó, J. J. Mañes   +2 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Correction: Microalgae for bioremediation: advances, challenges, and public perception on genetic engineering. [PDF]

BMC Plant Biol
Calatrava V, Gonzalez-Ballester D, Dubini A.   +2 more
europepmc   +1 more source