Results 281 to 290 of about 1,062,704 (335)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Tools for genetic engineering and gene expression control in Novosphingobium aromaticivorans and Rhodobacter sphaeroides. [PDF]

Appl Environ Microbiol
Hall AN, Hall BW, Kinney KJ, Olsen GG, Banta AB, Noguera DR, Donohue TJ, Peters JM.   +7 more
europepmc   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Development of a Pre-Modification Strategy to Overcome Restriction-Modification Barriers and Enhance Genetic Engineering in <i>Lactococcus lactis</i> for Nisin Biosynthesis. [PDF]

Int J Mol Sci
Chen C, Zhang Y, Chen R, Liu K, Wu H, Qiao J, Caiyin Q.   +6 more
europepmc   +1 more source

Social problems of genetic engineering [PDF]

, 2016
Franchevska, H., Фарнчевська, Г.   +1 more
core  

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Teaching old dogs new tricks: genetic engineering methanogens. [PDF]

Appl Environ Microbiol
Myers T, Myers T, Dykstra CM.
europepmc   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Genetic Engineering for Enhancing Sugarcane Tolerance to Biotic and Abiotic Stresses. [PDF]

Plants (Basel)
Kumar T, Wang JG, Xu CH, Lu X, Mao J, Lin XQ, Kong CY, Li CJ, Li XJ, Tian CY, Ebid MHM, Liu XL, Liu HB.   +12 more
europepmc   +1 more source

Specific promoters for genetic engineering of the rubber tree; molecular and functional analysis : [Draft] [PDF]

, 2004
Cambillau, Laurence, Chrestin, Hervé, Montoro, Pascal, Narangajavana, Jarunya, Puangkosol, N., Pujade-Renaud, Valérie, Sanier, Christine, Tharreau, Didier   +7 more
core