Results 301 to 310 of about 5,695,316 (423)

Genetic engineering drives the breakthrough of pig models in liver disease research. [PDF]

Liver Res
Xu C, Fang X, Xu X, Wei X.
europepmc   +1 more source

THE CONTRIBUTION OF GENETIC ENGINEERING TO THE UNDERSTANDING OF THE NEUROBIOLOGY OF OPIOID-REINFORCED BEHAVIOR

, 1996
A. Ennaceur, John P. Aggleton, P.J. Fray, Steven J. Cooper   +3 more
openalex   +1 more source

Nanoparticle mediated genetic engineering of plants.

Molecular Plant, 2019
J. Wang, E. G. Grandío, G. Newkirk, Gozde S. Demirer, Salwan Butrus, J. P. Giraldo, M. Landry   +6 more
semanticscholar   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Proteomic analysis reveals molecular changes following genetic engineering in Chlamydomonas reinhardtii. [PDF]

BMC Microbiol
Barolo L, Abbriano RM, Commault AS, Padula MP, Pernice M.   +4 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Genetic engineering, including genome editing, for enhancing broad-spectrum disease resistance in crops. [PDF]

Plant Commun
Han X, Li S, Zeng Q, Sun P, Wu D, Wu J, Yu X, Lai Z, Milne RJ, Kang Z, Xie K, Li G.   +11 more
europepmc   +1 more source

Genetic engineering strategies for biotic and abiotic stress tolerance and quality enhancement in horticultural crops: a comprehensive review

3 Biotech, 2017
Nehanjali Parmar, Kunwar Harendra Singh, D. Sharma, L. Singh, Pankaj Kumar, J. Nanjundan, Y. Khan, D. Chauhan, A. Thakur   +8 more
semanticscholar   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Genomics, genetic engineering and artificial cells

Annals of Indian Academy of Neurology, 2010
Thomas Sanjeev
doaj