Results 251 to 260 of about 9,865,393 (383)

Efficiency enhancement of genetic algorithms via building-block-wise fitness estimation [PDF]

, 2004
Kumara Sastry, Martin Pelikán, David E. Goldberg   +2 more
openalex   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

A Versatile Enhanced Genetic Algorithm for Planar Array Design [PDF]

, 2004
Massimo Donelli, S. Caorsi, Francesco G. B. De Natale, D. Franceschini, Andrea Massa   +4 more
openalex   +1 more source

Genetic enhancement, post-persons and moral status: a reply to Buchanan

Journal of Medical Ethics, 2011
D. DeGrazia
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome. [PDF]

Am J Med Genet C Semin Med Genet, 2016
Lopez-Burks ME, Santos R, Kawauchi S, Calof AL, Lander AD.   +4 more
europepmc   +1 more source

Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8 [PDF]

, 2004
Robert H. Wallis, Karin J. Wallace, Stephan C. Collins, Martina A. McAteer, Karène Argoud, Marie Thérèse Bihoreau, Pamela J. Kaisaki, Dominique Gauguier   +7 more
openalex   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Faculty Opinions recommendation of Evolution of functionally conserved enhancers can be accelerated in large populations: a population-genetic model.

, 2002
Patricia Simpson
openalex   +2 more sources

Enhanced kinetics of genetically engineered Burkholderia cepacia: the role of vgb in the hypoxic metabolism of 2‐CBA [PDF]

, 2004
Meltem Urgun‐Demirtas, Krishna Pagilla, Benjamin C. Stark   +2 more
openalex   +1 more source