Results 91 to 100 of about 903,421 (269)

UHPLC-MS/MS-Based Metabolomics Identifies Freshness Biomarkers and Temporal Spoilage Threshold in Refrigerated Goose Meat

Foods
The dynamic metabolic landscape underlying goose meat quality deterioration during refrigerated storage remains incompletely elucidated. Here, ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)-based widely targeted ...
Wen Gao, Zhengfeng Cao, Qiang Bao, Qingping Tang, Zhu Bu, Guohong Chen, Bichun Li, Qi Xu   +7 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Identification of a locus on Agropyron cristatum chromosome 6P that interacts with wheat genes to produce yellow–green leaves

BMC Plant Biology
Background Wide hybridization is crucial for broadening the genetic basis of common wheat. Agropyron cristatum (2n = 4x = 28, PPPP), a wild relative of wheat, harbors numerous favorable genes for genetic improvement.
Kai Qi, Haiming Han, Yuqing Lu, Jinpeng Zhang, Shenghui Zhou, Baojin Guo, Weihua Liu, Xiuquan Li, Xinming Yang, Xu Liu, Lihui Li   +10 more
doaj   +1 more source

Root system architecture and drought adaptation: emerging tools and genetic insights

Frontiers in Plant Science
Strategic optimisation of Root System Architecture (RSA) represents a critical frontier for stabilising crop productivity amid increasingly unpredictable moisture-deficit regimes.
Vikender Kaur, Shashank Kumar Yadav, Bindu Yadav, Sukham Madaan, Munisha Kheralia, Viswanathan Chinnusamy   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Cross-species transferability and genetic diversity analysis in Linum species using microsatellite markers

Scientific Reports
The genus Linum comprises over 230 species, with L. usitatissimum valued for linen and oil, yet crop wild relatives (CWRs) remain underutilized due to limited availability and poor molecular characterization.
Vijaykumar Kailasrao Raut, Umakanta Ngangkham, Aneeta Yadav, Vikender Kaur, Pavan Kumar Malav, Ankit Saroha, Gyanendra Pratap Singh, Dhammaprakash Pandhari Wankhede, Mamta Singh   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Integration ATAC‐Seq and RNA‐Seq Analysis of Mammary Placodes in Erhualian and Bamaxiang Pigs Identified Candidate Genes Influencing Pig Teat Number Variation

Evolutionary Applications
Teat number is an important economic trait in pigs, affecting piglet health and survival. While numerous GWAS have identified candidate genes for teat number in Duroc, Landrace, and Large White pigs, the causal genes remain unclear, largely due to a lack
Chenxi Liu, Ruihua Huang, Nengjing Jiang, Wuduo Zhou, Qian Liu, Taoran Du, Qian Zhang, Jinfeng Ma, Qingbo Zhao, Pinghua Li   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source