Results 121 to 130 of about 2,075,021 (307)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Pollen–pistil interactions in divergent wide crosses lead to spatial and temporal pre-fertilization reproductive barrier in flax (Linum usitatissimum L.)

Scientific Reports
Linseed, has been a source of natural fiber for textile industries since its domestication. However, despite being the potential source of trait reservoir, the use of Linum wild genetic resources for the improvement of economic traits are not exploited ...
Vijaykumar Kailasrao Raut, Aneeta Yadav, Vikender Kaur, Mahesh Rao, Pooja Pathania, Dhammaprakash Wankhede, Mamta Singh, Gyanendra Pratap Singh   +7 more
doaj   +1 more source

CRISPR-associated sequence diversity within Xanthomonas albilineans, the causal agent of leaf scald disease of sugarcane [PDF]

, 2012
Co-ordinated efforts to collect and maintain cotton genetic resources have increased over the last 100 years to insure the worldwide economic value of cotton fibre and cotton by-products.
Bolot, Stéphanie, Carrère, Sébastien, Cociancich, Stéphane, Gouzy, Jérôme, Marguerettaz, Mélanie, Pieretti, Isabelle, Rott, Philippe, Royer, Monique   +7 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

UHPLC-MS/MS-Based Metabolomics Identifies Freshness Biomarkers and Temporal Spoilage Threshold in Refrigerated Goose Meat

Foods
The dynamic metabolic landscape underlying goose meat quality deterioration during refrigerated storage remains incompletely elucidated. Here, ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)-based widely targeted ...
Wen Gao, Zhengfeng Cao, Qiang Bao, Qingping Tang, Zhu Bu, Guohong Chen, Bichun Li, Qi Xu   +7 more
doaj   +1 more source

Modern approaches for breeding high quality apples with durable resistance to scab, powdery mildew and fire blight [PDF]

, 2008
New methods to allow for more precise selection of tree and fruit characters in breeding programmes were developed in recent years. Marker-assisted selection (MAS) is common practice in the ACW apple breeding programme at Wädenswil.
Duffy, Brion, Frey, Jürg, Kellerhals, Markus, Patocchi, Andrea   +3 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Integration ATAC‐Seq and RNA‐Seq Analysis of Mammary Placodes in Erhualian and Bamaxiang Pigs Identified Candidate Genes Influencing Pig Teat Number Variation

Evolutionary Applications
Teat number is an important economic trait in pigs, affecting piglet health and survival. While numerous GWAS have identified candidate genes for teat number in Duroc, Landrace, and Large White pigs, the causal genes remain unclear, largely due to a lack
Chenxi Liu, Ruihua Huang, Nengjing Jiang, Wuduo Zhou, Qian Liu, Taoran Du, Qian Zhang, Jinfeng Ma, Qingbo Zhao, Pinghua Li   +9 more
doaj   +1 more source