Results 51 to 60 of about 2,075,021 (307)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Mapping and functional verification of leaf yellowing genes in watermelon during whole growth period

Frontiers in Plant Science, 2022
Increasing light energy utilization efficiency is an effective way to increase yield and improve quality of watermelon. Leaf is the main place for photosynthesis, and the color of leaf is directly related to the change of photosynthesis.
Yingchun Zhu, Yingchun Zhu, Gaopeng Yuan, Yifan Wang, Guolin An, Weihua Li, Junpu Liu, Junpu Liu, Dexi Sun   +8 more
doaj   +1 more source

HandyBroker - An intelligent product-brokering agent for M-commerce applications with user preference tracking [PDF]

, 2002
One of the potential applications for agent-based systems is m-commerce. A lot of research has been done on making such systems intelligent to personalize their services for users.
Aylett, Chon Seng Ngoo, Crabtree, Fangming Zhu, Finin, Maes, Morris, Nwana, Nwana, Pant, Sheth, Soltysiak, Soltysiak, Steven Guan, Zhu   +14 more
core   +2 more sources

A 16S RNA Analysis of Yangzhou Geese with Varying Body Weights: Gut Microbial Difference and Its Correlation with Body Weight Parameters

Animals
China is a major goose-raising country, and the geese industry plays a significant role in animal husbandry. Therefore, goose growth performance (body weight) is a critical topic.
Xinlei Xu, Suyu Fan, Hao Wu, Haoyu Li, Xiaoyu Shan, Mingfeng Wang, Yang Zhang, Qi Xu, Guohong Chen   +8 more
doaj   +1 more source

Development and optimization of NIRS prediction models for simultaneous multi-trait assessment in diverse cowpea germplasm

Frontiers in Nutrition, 2022
Cowpea (Vigna unguiculata (L.) Walp.) is one such legume that can facilitate achieving sustainable nutrition and climate change goals. Assessing nutritional traits conventionally can be laborious and time-consuming.
Siddhant Ranjan Padhi, Racheal John, Arti Bartwal, Kuldeep Tripathi, Kavita Gupta, Dhammaprakash Pandhari Wankhede, Gyan Prakash Mishra, Sanjeev Kumar, Jai Chand Rana, Amritbir Riar, Rakesh Bhardwaj   +10 more
doaj   +1 more source

Modelling epistasis in genetic disease using Petri nets, evolutionary computation and frequent itemset mining [PDF]

, 2010
Petri nets are useful for mathematically modelling disease-causing genetic epistasis. A Petri net model of an interaction has the potential to lead to biological insight into the cause of a genetic disease.
Beretta, Lorenzo, Mayo, Michael
core   +2 more sources

AN EXPERIMENTAL EVALUATION OF GENETIC CORRELATION [PDF]

Genetics, 1973
ABSTRACT Heritability and genetic correlations realized from both single-trait and antagonistic index selection were compared with paternal half-sib estimates. Primary attention was focused on the genetic correlation between six-week body weight and six-week tail length.
J J, Rutledge, E J, Eisen, J E, Legates
openaire   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Global transcriptome analysis reveals resistance genes in the early response of common bean (Phaseolus vulgaris L.) to Colletotrichum lindemuthianum

BMC Genomics
Background Disease can drastically impair common bean (Phaseolus vulgaris L.) production. Anthracnose, caused by the fungal pathogen Colletotrichum lindemuthianum (Sacc.
Yujie Chang, Yonghui Liu, Lanfen Wang, Shumin Wang, Jing Wu   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source