The rise of nutrigenomic retreats: Integrating culinary education, wellness, and personalized nutrition in the era of genomic health. [PDF]
Caglas R, Yilmaz V.
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Prenatal determinants of fetal programming in dairy cattle: A mini-review. [PDF]
Oladele AM +3 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Breastfeeding and prevention of childhood obesity: a narrative review of behavioral, hormonal, and microbiome programming. [PDF]
Abu Dheir N +11 more
europepmc +1 more source
Genetic expression programming for prediction of heat of hydration of the blended cements
This study presents a new approach based on Genetic Expression Programming (GEP) for modeling of variation of heat of hydration of Portland and blended cements. For that purpose, two different GEP models were developed to generate two mathematical equations.
Kayadelen, C. +4 more
openaire +3 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
GAMMA-RAY: A Fully Automated and Rapid System for High-Dimensional Multi-Phenotype Analysis Considering Population Structure. [PDF]
Kim T, Song J, Joo JWJ.
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
RATEX: A Scalable RNA-Based Platform for Logical and Multi-Layered Cellular Programming. [PDF]
Goh H, Kang H, Kim C, Kim J.
europepmc +1 more source

