Results 151 to 160 of about 56,733 (259)

Does early-life respiratory syncytial virus infection induce epigenetic changes that promote asthma development? [PDF]

Front Allergy
Pischedda S, Gómez-Carballa A, Martinón-Torres F, Salas A.   +3 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Adaptive multi-omics integration framework for breast cancer survival analysis. [PDF]

Sci Rep
Hasanzadeh E, Charkari NM.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Editorial: Expanding horizons in stress research-innovative paradigms and new directions in 2025. [PDF]

Neurobiol Stress
Schmidt MV, Reagan L.
europepmc   +1 more source

Genetic Programming Techniques for Regular Expression inference from Examples

, 2017
In the recent years, Machine Learning techniques have emerged as a new way to obtain solutions for a given problem, the novelty of the Machine Learning approach lies in the ability to automatically learn solutions by only looking at the observations of phenomena or examples of the expected behaviour.
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Modeling mechanical properties of rubberized concrete using gene expression programming (GEP) and random forest: a comparative study. [PDF]

Sci Rep
Sheraz M, Talha M, Alam M, Farhan M, Ul Haq Z, Rashid M, Alabduljabbar H, Ahmad F.   +7 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Double-strand break-free epigenetic programming: a safer path for T-cell therapies. [PDF]

Signal Transduct Target Ther
Deng L, Yang Y, El-Osta A, El-Osta A.
europepmc   +1 more source