Results 61 to 70 of about 172,998 (215)

Genes, Cognition, and Their Interplay in Methamphetamine Use Disorder

Biomolecules
Methamphetamine use disorder is a pressing global health issue, often accompanied by significant cognitive deficits that impair daily functioning and quality of life and complicate treatment.
Ramisha Khan, Alyna Turner, Michael Berk, Ken Walder, Susan Rossell, Alexandre A. Guerin, Jee Hyun Kim   +6 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Genetic monogamy in high density populations of a threatened Mediterranean rodent

Scientific Reports
Monogamous mammal species often exhibit flexible mating strategies in response to socio-ecological factors such as population density, though the extent of this flexibility remains unclear.
Ricardo Pita, José Jiménez, Joana Paupério, Benigno Cienfuegos, Alejandro Chamizo de Castro, Joshua Díaz-Caballero, João Queirós, Clara Ferreira, François Mougeot, Alfredo Anega, María Jesús Palacios, Juan José Luque-Larena   +11 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Container cloud resource prediction based on APMSSGA-LSTM

大数据, 2019
With the development and application of container cloud,the demand for high concurrency,high availability,high flexibility,and high flexibility of resources is becoming more and more intense.After investigating the current research status of container ...
Xiaolan XIE, Zhengzheng ZHANG, Qiangqing ZHENG, Chaoquan CHEN   +3 more
doaj  

The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility

Nature Communications, 2017
The factors that limit the nutrient flexibility of cells remain largely unknown. Here, the authors identify the glutamate/cysteine antiporter xCT in a genetic screen for glucose dependency and show it determines the ability of cells to survive under ...
Chun-Shik Shin, Prashant Mishra, Jeramie D. Watrous, Valerio Carelli, Marilena D’Aurelio, Mohit Jain, David C. Chan   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Social learning of vocal structure in a nonhuman primate?

BMC Evolutionary Biology, 2011
Background Non-human primate communication is thought to be fundamentally different from human speech, mainly due to vast differences in vocal control.
Lemasson Alban, Ouattara Karim, Petit Eric J, Zuberbühler Klaus   +3 more
doaj   +1 more source