Results 241 to 250 of about 1,196,074 (333)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

A comprehensive genetic map of cytokine responses in Lyme borreliosis. [PDF]

open access: yesNat Commun
Botey-Bataller J   +16 more
europepmc   +1 more source

Additional file 2: of An “Axiom Cajanus SNP Array” based high density genetic map and QTL mapping for high-selfing flower and seed quality traits in pigeonpea

open access: gold, 2019
Pooja Yadav   +6 more
openalex   +1 more source

An integrated genetic map of the pearl locus of mouse chromosome 13. [PDF]

open access: hybrid, 1996
Albert Seymour   +7 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

High-resolution genetic map and SNP chip for molecular breeding in Panax ginseng, a tetraploid medicinal plant. [PDF]

open access: yesHortic Res
Cho W   +17 more
europepmc   +1 more source

Construction of A GBS-Based High-Density Genetic Map and Flower Color-Related Loci Mapping in Grasspea (Lathyrus sativus L.). [PDF]

open access: yesPlants (Basel), 2022
Hao X   +9 more
europepmc   +1 more source

Alzheimer's genetic map [PDF]

open access: yesNature Biotechnology, 2011
openaire   +1 more source

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