Results 101 to 110 of about 5,464,915 (400)

Allele polymorphism of alkaline, acid soluble phosphatase genes and vitamin D-binding protein in postmenopausal osteoporosis

open access: yesТерапевтический архив, 2004
Aim. To study polymorphism of genes involved in mechanisms regulating metabolism of bone tissue: alkaline (ALPL) and acid (ACPI) phosphatases, vitamin D-bindingprotein (GC); to ascertain associations of their genotypes and alleles with osteoporosis (OP ...
M Yu Krylov   +3 more
doaj  

Distribution of powdery mildew resistance genes in the Kazakhstan apple cultivar collection [PDF]

open access: yesBrazilian Journal of Biology
The monogenic resistance to powdery mildew (caused by Podosphaera leucotricha) of apple trees is crucial when selecting them. DNA markers allow it to differentiate apple cultivars by individual resistance traits and determine prospective genotypes with ...
K. Galymbek   +6 more
doaj   +1 more source

Variability of ACOX1 Gene Polymorphisms across Different Horse Breeds with Regard to Selection Pressure

open access: yesAnimals, 2020
The ACOX1 gene encodes peroxisomal acyl-coenzyme A oxidase 1, the first enzyme in the fatty acid β-oxidation pathway, which could be significant for organisms exposed to long periods of starvation and harsh living conditions.
Grzegorz Myćka   +4 more
doaj   +1 more source

Prolactin receptor gene ( PRLR ) role in swine reproduction [PDF]

open access: yesTrakia Journal of Sciences, 2019
PRLR gene has been studied as a candidate gene for litter size in swine because of prolactin biological functions and their association with reproduction. Prolactin receptor gene is mapped on porcine chromosome 16.
Zh. Sabev
doaj   +1 more source

Genetic markers for the epidemiology of tuberculosis

open access: bronzeResearch in Microbiology, 1992
J. D. A. van Embden   +3 more
openalex   +4 more sources

Homozygosity and risk of childhood death due to invasive bacterial disease. [PDF]

open access: yes, 2009
BACKGROUND: Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance linkage between a marker and

core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

HLA Pharmacogenetic Markers of Drug Hypersensitivity in a Thai Population

open access: yesFrontiers in Genetics, 2018
Severe cutaneous adverse drug reactions (SCARs) including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reactions with eosinophilia and systemic symptoms (DRESS) are potentially life-threatening cutaneous reactions caused by ...
Nontaya Nakkam   +9 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

European pig genetic diversity: a minireview*

open access: yesAnimal, 2009
An evaluation of the European pig diversity has been carried on by several countries, with the support of the European Union over the period of 1994 to 2000. This article presents an overview of the results of this investigation, focussing on two genetic
L. Ollivier
doaj   +1 more source

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