Results 111 to 120 of about 1,500,690 (354)

Assessment of genetic diversity of Prunus salicina 'Shazikongxinli' by morphological traits and molecular markers [PDF]

, 2023
Gui Wang, Ruirui Li, Maohong Wu, Feihong Ren, Lili Wang, Guang Qiao   +5 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Genetic variability and relationship among different accessions of Froriepia subpinata Bail (Gijavash) an endangered medicinal plant from Iran revealed by ISSR and IRAP markers

, 2021
Abbas Jorkesh, Yousef Hamidoghli, J. A. Olfati, Habibollah Samizadeh Lahiji, Davood Bakhshi   +4 more
openalex   +2 more sources

Genome-Wide Fine-Mapping Of Diabetic Traits [PDF]

, 2013
Type 2 diabetes results from both genes and the environment. Mapping genetic loci in animal models can help identify genes that are involved in type 2 diabetes to better understand the disease.
Baur, Brittany
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Genetic diversity of tropical-adapted onion germplasm assessed by RAPD markers [PDF]

, 2012
Maria do Desterro Mendes dos Santos, Carlos Francisco Ragassi, Maria Esther de Noronha Fonseca, Anne Gizelle R Buzar, V. R. Oliveira, Paulo Melo, L. S. Boiteux   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Corrigendum: The association between FokI vitamin D receptor polymorphisms with metabolic syndrome among pregnant Arab women

Frontiers in Endocrinology, 2023
Maysa Alzaim, Nasser M. Al-Daghri, Shaun Sabico, Mona A. Fouda, Sara Al-Musharaf, Malak N. K. Khattak, Abdul Khader Mohammed, Abdulrahman Al-Ajlan, Dalal N. Binjawhar, Richard Wood   +9 more
doaj   +1 more source

Structural variations in livestock genomes and their associations with phenotypic traits: a review

Frontiers in Veterinary Science
Genomic structural variation (SV) refers to differences in gene sequences between individuals on a genomic scale. It is widely distributed in the genome, primarily in the form of insertions, deletions, duplications, inversions, and translocations. Due to
Yinghui Chen, Muhammad Zahoor Khan, Xinrui Wang, Huili Liang, Wei Ren, Xiyan Kou, Xiaotong Liu, Wenting Chen, Yongdong Peng, Changfa Wang   +9 more
doaj   +1 more source